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Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His), Biotinylated
(Synonyms: Car9, Ca9) Copy Product InfoSynonyms: Car9, Ca9
Catalog No. TMPY-07203 Copy Product Info
Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 Cells. The accession number is Q8VHB5.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $172 | 7-10 days | 7-10 days | |
| 10 µg | $298 | 7-10 days | 7-10 days | |
| 20 µg | $497 | 7-10 days | 7-10 days | |
| 50 µg | $816 | 7-10 days | 7-10 days | |
| 100 µg | $1,360 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 Cells. The accession number is Q8VHB5. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q8VHB5 |
| Construction | A DNA sequence encoding the Mouse CA9 (NP_647466.2) (Met1-Asp390) was expressed with a polyhistidine tag at the C-terminus. The purified protein was biotinylated in vitro. |
| Protein Purity | ≥ 95% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Please refer to the lot-specific COA. |
| Synonyms | Car9, Ca9 |
| Research Background | Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Molecular Weight | 40.3 kDa (predicted); 51 kDa (reducing contition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His), Biotinylated chemical structure | Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His), Biotinylated molecular weight
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