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Apixaban 13C,d3

Name: Apixaban 13C,d3
Brand: TargetMol
SKU: T10349
Rating: 4.5 (1 reviews)

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Catalog No. T10349Cas No. 1261393-15-0

Alias BMS-562247-01 13CD3, BMS-56224701 13CD3, Apixaban 13CD3

Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor Xa and is used in thromboembolism studies

Apixaban 13C,d3

😃Good

Catalog No. T10349Alias BMS-562247-01 13CD3, BMS-56224701 13CD3, Apixaban 13CD3Cas No. 1261393-15-0

Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor Xa and is used in thromboembolism studies

Pack Size	Price	Availability	Quantity
1 mg	$123	7-10 days
5 mg	$587	7-10 days

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Product Introduction

Bioactivity

Description	Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor Xa and is used in thromboembolism studies
Synonyms	BMS-562247-01 13CD3, BMS-56224701 13CD3, Apixaban 13CD3

Chemical Properties

Molecular Weight	463.51
Formula	C₂₅H₂₅N₅O₄
Cas No.	1261393-15-0
Smiles	O=C1C=2N(N=C(C(N)=O)C2CCN1C3=CC=C(C=C3)N4C(=O)CCCC4)C5=CC=C(O[13C]([2H])([2H])[2H])C=C5
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 3 mg/mL (6.47 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1575 mL	10.7873 mL	21.5745 mL	107.8725 mL
5 mM	0.4315 mL	2.1575 mL	4.3149 mL	21.5745 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc