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Dihydrolipoic acid

Name: Dihydrolipoic acid
Brand: TargetMol
SKU: T21233
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21233Cas No. 462-20-4

Alias USAF XR-12, Reduced thioctic acid, Reduced lipoic acid, DHLA, 6,8-Dihydrothioctic acid

Dihydrolipoic acid (USAF XR-12), a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.

Dihydrolipoic acid

🥰Excellent

Purity: 97.51%

Catalog No. T21233Alias USAF XR-12, Reduced thioctic acid, Reduced lipoic acid, DHLA, 6,8-Dihydrothioctic acidCas No. 462-20-4

Pack Size	Price	Availability	Quantity
25 mg	$33	In Stock
1 mL x 10 mM (in DMSO)	$36	In Stock

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Batch Information

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Purity:97.51%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Dihydrolipoic acid (USAF XR-12), a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.
Synonyms	USAF XR-12, Reduced thioctic acid, Reduced lipoic acid, DHLA, 6,8-Dihydrothioctic acid

Chemical Properties

Molecular Weight	208.34
Formula	C₈H₁₆O₂S₂
Cas No.	462-20-4
Smiles	C(C(CCS)S)CCCC(O)=O
Relative Density.	1.136 g/cm3. Temperature:20 °C.
Color	Transparent
Appearance	Liquid

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (239.99 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.7998 mL	23.9992 mL	47.9985 mL	239.9923 mL
5 mM	0.9600 mL	4.7998 mL	9.5997 mL	47.9985 mL
10 mM	0.4800 mL	2.3999 mL	4.7998 mL	23.9992 mL
20 mM	0.2400 mL	1.2000 mL	2.3999 mL	11.9996 mL
50 mM	0.0960 mL	0.4800 mL	0.9600 mL	4.7998 mL
100 mM	0.0480 mL	0.2400 mL	0.4800 mL	2.3999 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc