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Anti-FOLR2 Polyclonal Antibody (Synonyms: β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1|...)
Catalog No. TMAB-00696 Copy Product Info
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Anti-FOLR2 Polyclonal Antibody is a Rabbit antibody targeting FOLR2. Anti-FOLR2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-FOLR2 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00696
Synonyms β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR
Anti-FOLR2 Polyclonal Antibody is a Rabbit antibody targeting FOLR2. Anti-FOLR2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-FOLR2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-FOLR2 Polyclonal Antibody is a Rabbit antibody targeting FOLR2. Anti-FOLR2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Horse) |
| Verified Activity | 1. Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-FOLR2 Polyclonal Antibody, Unconjugated (TMAB-00696) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Sample: Lane 1: Recombinant human FOLR2 protein, N-His Primary: Anti-FOLR2 (TMAB-00696) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 25 kDa Observed band size: 25 kDa   |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Secreted. |
| Tissue Specificity | Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human Folate receptor |
| Antigen Species | Human |
| Gene Name | FOLR2 |
| Gene ID | |
| Protein Name | Folate receptor beta |
| Uniprot ID | |
| Biology Area | Vitamins / minerals,Vitamins / Minerals |
| Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. |
| Molecular Weight | Theoretical: 25 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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