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TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated
(Synonyms: Tumor-associated calcium signal transducer 2, TROP2, TACSTD2, Membrane component chromosome 1 surface marker 1, Cell surface glycoprotein Trop-2) Copy Product InfoSynonyms: Tumor-associated calcium signal transducer 2, TROP2, TACSTD2, Membrane component chromosome 1 surface marker 1, Cell surface glycoprotein Trop-2
Catalog No. TMPJ-00204 Copy Product Info
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 40-60 KDa and the accession number is P09758.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $129 | 35 days | 35 days | |
| 10 μg | $213 | 35 days | 35 days | |
| 20 μg | $355 | 35 days | 35 days | |
| 50 μg | $625 | 35 days | 35 days | |
| 100 μg | $963 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | 1. Loaded Anti-Human TROP-2 mAb-Fc on Protein A Biosensor, can bind Biotinylated Human TROP-2-Avi-His with an affinity constant of 0.49 nM as determined in BLI assay. (Regularly tested)
2. Immobilized Biotinylated Human TROP-2-Avi-His at 1μg/ml (100 μl/well) can bind Anti-Human TROP-2 mAb. The ED50 of Anti-Human TROP-2 mAb is 4.19 ng/ml. (Regularly tested) |
| Description | Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 40-60 KDa and the accession number is P09758. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-Avi-6xHis |
| Accession Number | P09758 |
| Amino Acid | His27-Thr274 |
| Construction | His27-Thr274 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Tumor-associated calcium signal transducer 2, TROP2, TACSTD2, Membrane component chromosome 1 surface marker 1, Cell surface glycoprotein Trop-2 |
| Research Background |
| Molecular Weight | 40-60 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated chemical structure | TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated molecular weight
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