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CD19 Protein, Mouse, Recombinant (hFc)

(Synonyms: Cd19) Copy Product Info

Synonyms: Cd19

Catalog No. TMPY-07198 Copy Product Info
CD19 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P25918.
CD19 Protein, Mouse, Recombinant (hFc)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$77-In Stock
10 µg$1267-10 days7-10 days
20 µg$1987-10 days7-10 days
50 µg$3977-10 days7-10 days
100 µg$7967-10 days7-10 days
200 µg$1,2007-10 days7-10 days
500 µg$2,5907-10 days7-10 days
1 mg$5,2807-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Immobilized Recombinant Mouse CD19 Protein (Fc Tag) at 2 μg/mL (100 μL/well) can bind CD19 Antibody, Rabbit MAb, the EC50 is 30-100 ng/mL.
Description
CD19 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P25918.
Species
Mouse
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP25918
ConstructionA DNA sequence encoding the Mouse CD19 (NP_033974.2) (Arg19-Gly287) was expressed with a hFc tag at the C-terminus.
Protein Purity
≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
ReconstitutionPlease refer to the lot-specific COA.
SynonymsCd19
Research Background
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Chemical Properties
Molecular Weight56.3 kDa (predicted); 131.9 kDa (reducing contition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: CD19 Protein, Mouse, Recombinant (hFc) chemical structure | CD19 Protein, Mouse, Recombinant (hFc) molecular weight