CD19 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPY-07198 Copy Product Info

CD19 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P25918.

CD19 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPY-07198

Copy Product Info

CD19 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P25918.

Pack Size	Price	USA Stock	Global Stock
5 μg	$77	-	In Stock
10 μg	$126	7-10 days	7-10 days
20 μg	$198	7-10 days	7-10 days
50 μg	$397	7-10 days	7-10 days
100 μg	$796	7-10 days	7-10 days
200 μg	$1,200	7-10 days	7-10 days
500 μg	$2,590	7-10 days	7-10 days
1 mg	$5,280	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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COA User Guide of Recombinant Proteins

Product Information

Biological Activity	Immobilized Recombinant Mouse CD19 Protein (Fc Tag) at 2 μg/mL (100 μL/well) can bind CD19 Antibody, Rabbit MAb, the EC50 is 30-100 ng/mL.
Description	CD19 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P25918.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P25918
Synonyms	Cd19
Construction	A DNA sequence encoding the Mouse CD19 (NP_033974.2) (Arg19-Gly287) was expressed with a hFc tag at the C-terminus.
Protein Purity	≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
Molecular Weight	56.3 kDa (predicted); 131.9 kDa (reducing contition)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

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