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Tumour-associated MUC1 epitope
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Catalog No. T80919Cas No. 129437-45-2
Tumor-associated MUC1 epitope, a biologically active peptide, is the distinctive feature of MUC1 mucin—a significantly glycosylated type I transmembrane glycoprotein. Its extracellular domain comprises variable numbers of tandem repeats (VNTR) of a 20 amino acid sequence. This peptide is overexpressed on the surface of various human adenocarcinomas and hematological malignancies like multiple myeloma and B-cell lymphoma, rendering MUC1 a widely relevant target for immunotherapeutic approaches.
Tumour-associated MUC1 epitope
😃Good
Catalog No. T80919Cas No. 129437-45-2
Tumor-associated MUC1 epitope, a biologically active peptide, is the distinctive feature of MUC1 mucin—a significantly glycosylated type I transmembrane glycoprotein. Its extracellular domain comprises variable numbers of tandem repeats (VNTR) of a 20 amino acid sequence. This peptide is overexpressed on the surface of various human adenocarcinomas and hematological malignancies like multiple myeloma and B-cell lymphoma, rendering MUC1 a widely relevant target for immunotherapeutic approaches.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Bioactivity
Chemical Properties
| Description | Tumor-associated MUC1 epitope, a biologically active peptide, is the distinctive feature of MUC1 mucin—a significantly glycosylated type I transmembrane glycoprotein. Its extracellular domain comprises variable numbers of tandem repeats (VNTR) of a 20 amino acid sequence. This peptide is overexpressed on the surface of various human adenocarcinomas and hematological malignancies like multiple myeloma and B-cell lymphoma, rendering MUC1 a widely relevant target for immunotherapeutic approaches. |
| Molecular Weight | 1887.02 |
| Formula | C80H127N25O28 |
| Cas No. | 129437-45-2 |
| Sequence | Pro-Asp-Thr-Arg-Pro-Ala-Pro-Gly-Ser-Thr-Ala-Pro-Pro-Ala-His-Gly-Val-Thr-Ser-Ala |
| Sequence Short | PDTRPAPGSTAPPAHGVTSA |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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