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Tumour-associated MUC1 epitope

Catalog No. T80919 Copy Product Info
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Tumor-associated MUC1 epitope, a biologically active peptide, is the distinctive feature of MUC1 mucin—a significantly glycosylated type I transmembrane glycoprotein. Its extracellular domain comprises variable numbers of tandem repeats (VNTR) of a 20 amino acid sequence. This peptide is overexpressed on the surface of various human adenocarcinomas and hematological malignancies like multiple myeloma and B-cell lymphoma, rendering MUC1 a widely relevant target for immunotherapeutic approaches.

Tumour-associated MUC1 epitope

Copy Product Info
🥰Excellent
Catalog No. T80919

Tumor-associated MUC1 epitope, a biologically active peptide, is the distinctive feature of MUC1 mucin—a significantly glycosylated type I transmembrane glycoprotein. Its extracellular domain comprises variable numbers of tandem repeats (VNTR) of a 20 amino acid sequence. This peptide is overexpressed on the surface of various human adenocarcinomas and hematological malignancies like multiple myeloma and B-cell lymphoma, rendering MUC1 a widely relevant target for immunotherapeutic approaches.

Tumour-associated MUC1 epitope
Cas No. 129437-45-2
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Product Introduction

Bioactivity
Description
Tumor-associated MUC1 epitope, a biologically active peptide, is the distinctive feature of MUC1 mucin—a significantly glycosylated type I transmembrane glycoprotein. Its extracellular domain comprises variable numbers of tandem repeats (VNTR) of a 20 amino acid sequence. This peptide is overexpressed on the surface of various human adenocarcinomas and hematological malignancies like multiple myeloma and B-cell lymphoma, rendering MUC1 a widely relevant target for immunotherapeutic approaches.
Chemical Properties
Molecular Weight1887.02
FormulaC80H127N25O28
Cas No.129437-45-2
SmilesC(=O)([C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC(CNC(=O)[C@H]2N(C([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]4CCCN4)CC(O)=O)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CCC3)C)=O)CCC2)=O)CO)=O)[C@@H](C)O)=O)C)=O)CCC1)N5[C@H](C(N[C@H](C(N[C@@H](CC6=CN=CN6)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CO)=O)[C@@H](C)O)=O)[C@@H](C)C)=O)=O)=O)C)=O)CCC5
SequencePro-Asp-Thr-Arg-Pro-Ala-Pro-Gly-Ser-Thr-Ala-Pro-Pro-Ala-His-Gly-Val-Thr-Ser-Ala
Sequence ShortPDTRPAPGSTAPPAHGVTSA
Storage & Solubility Information
StorageShipping with blue ice/Shipping at ambient temperature.

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Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

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