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Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody

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Catalog No. TMAC-01439

Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FANCD2 (Ser222). Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody can be used in WB.

Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody

Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody

😃Good
Catalog No. TMAC-01439
Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FANCD2 (Ser222). Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2177-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FANCD2 (Ser222). Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundRequired for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 222 (G-D-S(p)-Q-H) derived from Human FANCD2
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 166 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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