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IL-22RA1 Protein, Mouse, Recombinant (hFc)
(Synonyms: zcytoR11, IL-TIF-R1, IL-22R-α-1, IL-22R-alpha-1, IL-22RA1, IL22R1, IL-22R α1, IL22R, CRF2-9) Copy Product InfoSynonyms: zcytoR11, IL-TIF-R1, IL-22R-α-1, IL-22R-alpha-1, IL-22RA1, IL22R1, IL-22R α1, IL22R, CRF2-9
Catalog No. TMPK-01071 Copy Product Info
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 51.1 kDa and the accession number is Q80XZ4.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $82 | 7-10 days | 7-10 days | |
| 10 μg | $132 | 7-10 days | 7-10 days | |
| 20 μg | $217 | 7-10 days | 7-10 days | |
| 50 μg | $428 | 7-10 days | 7-10 days | |
| 100 μg | $721 | 7-10 days | 7-10 days | |
| 200 μg | $1,280 | 7-10 days | 7-10 days | |
| 500 μg | $2,890 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Biotinylated Mouse IL-22, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Mouse IL-22R alpha 1, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. |
| Description | Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 51.1 kDa and the accession number is Q80XZ4. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q80XZ4 |
| Construction | His16-Ala228 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | zcytoR11, IL-TIF-R1, IL-22R-α-1, IL-22R-alpha-1, IL-22RA1, IL22R1, IL-22R α1, IL22R, CRF2-9 |
| Research Background | Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. |
| Molecular Weight | 51.1 kDa (predicted). Due to glycosylation, the protein migrates to 65-68 kDa based on Tris-Bis PAGE result. |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
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Related Tags: IL-22RA1 Protein, Mouse, Recombinant (hFc) chemical structure | IL-22RA1 Protein, Mouse, Recombinant (hFc) molecular weight
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