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Polymyxin B Sulfate

🥰Excellent
Catalog No. T1100Cas No. 1405-20-5
Alias Poly-RX, Polymyxin B sulphate, Polymyxin B sulfate (1404-26-8 free base), PMB, Aerosporin

Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B Sulfate (Poly-RX) is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.

Polymyxin B Sulfate
Other Forms of Polymyxin B Sulfate:
Polymyxin BT786851404-26-8
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Polymyxin B Sulfate

🥰Excellent
Purity: 8331u/mg
Catalog No. T1100Alias Poly-RX, Polymyxin B sulphate, Polymyxin B sulfate (1404-26-8 free base), PMB, AerosporinCas No. 1405-20-5
Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B Sulfate (Poly-RX) is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
Pack SizePriceAvailabilityQuantity
500 mg$30In Stock
1 g$43In Stock
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Purity:8331u/mg
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Product Introduction

Bioactivity
Description
Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B Sulfate (Poly-RX) is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
SynonymsPoly-RX, Polymyxin B sulphate, Polymyxin B sulfate (1404-26-8 free base), PMB, Aerosporin
Chemical Properties
Molecular Weight1301.56
FormulaC56H100N16O17S
Cas No.1405-20-5
SmilesOS(O)(=O)=O.CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCN)NC1=O)[C@@H](C)O
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 50 mg/mL (38.42 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM0.7683 mL3.8415 mL7.6831 mL38.4154 mL
5 mM0.1537 mL0.7683 mL1.5366 mL7.6831 mL
10 mM0.0768 mL0.3842 mL0.7683 mL3.8415 mL
20 mM0.0384 mL0.1921 mL0.3842 mL1.9208 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

Polymyxin B SulfatePolymyxin BInhibitorinhibitE. coli strainBacterialantiendotoxinAntibioticantibacterialAntibacterial1404-26-8 free base1404-26-8
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