Select your Country or Region

  • TargetMol | Compound LibraryArgentinaArgentina
  • TargetMol | Compound LibraryAustraliaAustralia
  • TargetMol | Compound LibraryAustriaAustria
  • TargetMol | Compound LibraryBelgiumBelgium
  • TargetMol | Compound LibraryBrazilBrazil
  • TargetMol | Compound LibraryBulgariaBulgaria
  • TargetMol | Compound LibraryCroatiaCroatia
  • TargetMol | Compound LibraryCyprusCyprus
  • TargetMol | Compound LibraryCzechCzech
  • TargetMol | Compound LibraryDenmarkDenmark
  • TargetMol | Compound LibraryEgyptEgypt
  • TargetMol | Compound LibraryEstoniaEstonia
  • TargetMol | Compound LibraryFinlandFinland
  • TargetMol | Compound LibraryFranceFrance
  • TargetMol | Compound LibraryGermanyGermany
  • TargetMol | Compound LibraryGreeceGreece
  • TargetMol | Compound LibraryHong KongHong Kong
  • TargetMol | Compound LibraryHungaryHungary
  • TargetMol | Compound LibraryIcelandIceland
  • TargetMol | Compound LibraryIndiaIndia
  • TargetMol | Compound LibraryIrelandIreland
  • TargetMol | Compound LibraryIsraelIsrael
  • TargetMol | Compound LibraryItalyItaly
  • TargetMol | Compound LibraryJapanJapan
  • TargetMol | Compound LibraryKoreaKorea
  • TargetMol | Compound LibraryLatviaLatvia
  • TargetMol | Compound LibraryLebanonLebanon
  • TargetMol | Compound LibraryMalaysiaMalaysia
  • TargetMol | Compound LibraryMaltaMalta
  • TargetMol | Compound LibraryMoroccoMorocco
  • TargetMol | Compound LibraryNetherlandsNetherlands
  • TargetMol | Compound LibraryNew ZealandNew Zealand
  • TargetMol | Compound LibraryNorwayNorway
  • TargetMol | Compound LibraryPolandPoland
  • TargetMol | Compound LibraryPortugalPortugal
  • TargetMol | Compound LibraryRomaniaRomania
  • TargetMol | Compound LibrarySingaporeSingapore
  • TargetMol | Compound LibrarySlovakiaSlovakia
  • TargetMol | Compound LibrarySloveniaSlovenia
  • TargetMol | Compound LibrarySpainSpain
  • TargetMol | Compound LibrarySwedenSweden
  • TargetMol | Compound LibrarySwitzerlandSwitzerland
  • TargetMol | Compound LibraryTaiwan,ChinaTaiwan,China
  • TargetMol | Compound LibraryThailandThailand
  • TargetMol | Compound LibraryTurkeyTurkey
  • TargetMol | Compound LibraryUnited KingdomUnited Kingdom
  • TargetMol | Compound LibraryUnited StatesUnited States
  • TargetMol | Compound LibraryOther CountriesOther Countries
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Gap Junction Protein

Gap junctions are a specialized intercellular connection between a multitude of animal cell-types. They directly connect the cytoplasm of two cells, which allows various molecules, ions and electrical impulses to directly pass through a regulated gate between cells.One gap junction channel is composed of two connexons (or hemichannels), which connect across the intercellular space. Gap junctions are analogous to the plasmodesmata that join plant cells.

  • TAT-Gap19 acetate
    TP2110L
    TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the corresponding Cx43 GJCs.
    • $97
    In Stock
    Size
    QTY
  • Rotigaptide TFA(355151-12-1 free base)
    T16790L
    Rotigaptide TFA(355151-12-1 free base) is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide TFA(355151-12-1 free base) prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress.
    • $135
    In Stock
    Size
    QTY
  • Carbenoxolone disodium
    T09927421-40-1
    Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.
    • $32
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Gap 26
    T5192197250-15-0
    Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.
    • $79
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Meclofenamic acid
    T11990644-62-2
    Meclofenamic acid (Meclofenamate) is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic acid has anti-inflammatory activities.
    • Inquiry Price
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Carbenoxolone
    T77325697-56-3
    Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents the development of fatty liver disease.
    • $50
    Backorder
    Size
    QTY
  • Peptide5 TFA
    T78061
    Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury. Additionally, it suppresses the NLRP3 inflammasome, functioning as an anti-inflammatory agent [1] [2] [3].
    • Inquiry Price
    Size
    QTY
  • Gap19
    TP15631507930-57-5
    Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
    • $52
    In Stock
    Size
    QTY
  • Gap 27
    TP1333198284-64-9
    Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.
    • $48
    In Stock
    Size
    QTY
  • Carvedilol phosphate hemihydrate
    T0342610309-89-2
    Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.
    • $31
    In Stock
    Size
    QTY
  • Danegaptide Hydrochloride
    T19335943133-81-1
    Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) (GAP-134 Hydrochloride) is a selective modifier of the gap junction protein.
    • $47
    In Stock
    Size
    QTY
  • Larazotide acetate
    T15711881851-50-9
    Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.
    • $39
    In Stock
    Size
    QTY
  • Meclofenamic acid sodium
    T02606385-02-0
    Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
    • $33
    In Stock
    Size
    QTY