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TargetMol | Compound Library

Anti-Breast Cancer Compound Library

Catalog No. L2191

Breast cancer is an uncontrolled growth of breast cells. Among women, breast cancer is the second most common cancer diagnosed, after skin cancer (, and the second leading cause of cancer death, after lung cancer. In recent years, incidence rates have increased slightly (by 0.3% per year). There are several types of breast cancer, and they are broken into two main categories: noninvasive or in situ (ductal or lobular), and invasive (ductal or lobular). In addition, breast cancer can be categorized into four molecular subtypes: a "basal-like" subgroup with low estrogen receptor (ER)/progesterone receptor (PR)/human epidermal growth factor receptor 2 (HER2) and expression of basal cytokeratins (ER-PR-HER2-); a subgroup mainly driven by HER2 amplification and overexpression while being ER/PR low (ER-PR-HER2+); a luminal A group with high ER/PR and low HER2 (ER+PR+HER2-); a luminal B group with high ER/HER2 and low PR (ER+PR-HER2+). Depending on the caner's stage and molecular type, treatment options and prognostics of breast cancers are different: a combination of surgery, radiation therapy, chemotherapy, hormone therapy and/or administration of a targeted therapy (anti-HER2) or non-HER2 targeted therapy. Several potential targets for new breast cancer drugs have been identified in recent years. Drugs based on these targets, such as kinase inhibitors (AKT), and PD-L1, are now being studied to treat triple-negative breast cancers, either by themselves, or in combination with chemotherapy. TargetMol's Anti-Breast Cancer Compound Library collects 2440 compounds related to breast cancer, including all reported compounds with anti-breast cancer therapeutic effect, and compounds targeting related targets in signaling pathway (HER-2, VEGF, EGFR, PARP, CDK4/6, HSP, PD-1, SET7/9, BRCA, etc.). It is a power tool for breast cancer drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2191

Anti-Breast Cancer Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2440 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study;
  • Targets include HER-2, VEGF, EGFR, PARP, CDK4/6, HSP, PD-1, SET7/9, BRCA, etc.;
  • Some compounds have been in market or in clinical trials;
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Apoptosis
Autophagy
NF-κB
PI3K
CDK
EGFR
VEGFR
Reactive Oxygen Species
COX
PPAR
mTOR
Akt
Endogenous Metabolite
HDAC
PARP
AMPK
GSK-3
FGFR
Antibacterial
HSP
TGF-beta/Smad
PDGFR
ERK
FLT
Estrogen/progestogen Receptor
c-Kit
Src
Estrogen Receptor/ERR
IκB/IKK
DNA-PK
Parasite
DNA/RNA Synthesis
STAT
TNF
Wnt/beta-catenin
S6 Kinase
p38 MAPK
ATM/ATR
HER
Antioxidant
Progesterone Receptor
HIV Protease
Ferroptosis
Caspase
c-Met/HGFR
ALK
JNK
RIP kinase
IL Receptor
Aurora Kinase
Microtubule Associated
Antibiotic
PKC
PDK
Calcium Channel
Gamma-secretase
Cytochromes P450
Influenza Virus
NOD
Mitophagy
Potassium Channel
Bcr-Abl
PD-1/PD-L1
Topoisomerase
JAK
c-RET
Antifungal
Raf
MEK
IRAK
NO Synthase
PKA
ROS
Lipoxygenase
Bcl-2 Family
Dehydrogenase
IGF-1R
MAPK
PI4K
NOS
Chk
p53
MMP
Prostaglandin Receptor
Nrf2
Virus Protease
Casein Kinase
Beta Amyloid
TAM Receptor
Phosphatase
Tyrosine Kinases
PDE
Mitochondrial Metabolism
Epigenetic Reader Domain
GABA Receptor
FAK
NOD-like Receptor (NLR)
Androgen Receptor
c-Fms
Tyrosinase
HIF/HIF Prolyl-Hydroxylase
TRP/TRPV Channel
HSV
Sirtuin
Aromatase
Sodium Channel
HCV Protease
SIK
Drug Metabolite
TLR
Trk receptor
AChR
Syk
Ras
PROTACs
ROCK
PTEN
Interleukin
P-gp
transporter
5-HT Receptor
GPCR
Proteasome
Carbonic Anhydrase
Histone Methyltransferase
DYRK
Histone Demethylase
NADPH
Serine/threonin kinase
Adrenergic Receptor
PGE Synthase
Antiviral
MELK
PLK
HIF
Integrin
Adenosine Receptor
Pim
Serine Protease
Nucleoside Antimetabolite/Analog
Glucocorticoid Receptor
E1/E2/E3 Enzyme
Opioid Receptor
Cholinesterase (ChE)
SGK
Cannabinoid Receptor
Anti-infection
Chloride channel
Transferase
ADC Cytotoxin
RAAS
Histamine Receptor
Tie-2
Glutathione Peroxidase
Rho
PYK2
MAO
Aryl Hydrocarbon Receptor
IAP
CSF-1R
LDL
Glucosidase
Antifection
Fatty Acid Synthase
Hedgehog/Smoothened
CaMK
SARS-CoV
Free radical scavengers
Ephrin Receptor
MLK
ATPase
DHFR
ROR
BACE
GTPase
MRP
GNRH Receptor
HBV
Leukotriene Receptor
IRE1
DNA Alkylation
GluR
DUB
Wee1
BCRP
Survivin
LRRK2
Retinoid Receptor
Phospholipase
AhR
Kinesin
S1P Receptor
BTK
Mdm2
RAR/RXR
Dopamine Receptor
YAP
DNA Alkylator/Crosslinker
LTR
IFNAR
PERK
TOPK
c-Myc
Cholecystokinin Receptor
Cysteine Protease
Glutaminase
RANKL/RANK
Immunology/Inflammation related
ABC Transporter
FAAH
CCR
CXCR
cAMP
Indoleamine 2,3-Dioxygenase (IDO)
Beta-Secretase
MNK
STING
PAI-1
RSV
GPX
Reverse Transcriptase
Discoidin Domain Receptor (DDR)
Gap Junction Protein
Proton pump
NPC1L1
NUDIX hydrolase
MyD88
LPL Receptor
Reductase
Lipase
gp120/CD4
Melatonin Receptor
OCT
AAK1
Antifolate
Hck
Cell Cycle Arrest
Liver X Receptor
FXR
Glucokinase
Myosin
FLAP
UGT
PAFR
Haspin Kinase
GRK
NMDAR
DNA gyrase
Hexokinase
Smo
PROTAC Linker
PAK
ACK1
Endothelin Receptor
Somatostatin
Epoxide Hydrolase
KSP
DNA
Telomerase
SGLT
ATP Citrate Lyase
OXPHOS
Glutathione reductase
Acyltransferase
Aminopeptidase
Histone Acetyltransferase
Decarboxylase
cGAS
HuR
GST
Ligand for E3 Ligase
CRISPR/Cas9
Adenosine Deaminase
DAPK
Platelet aggregation
NADPH-oxidase
DNA Methyltransferase
APC/C
Thrombin
Protease-activated Receptor
ROS Kinase
CFTR
PKM
Monoamine Oxidase

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