Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK6/PIM1-IN-1 is a balanced, potent, dual CDK6 (IC50: 39 nM) and PIM1 (IC50: 88 nM) inhibitor. CDK6/PIM1-IN-1 showed inhibitory effect on CDK4 with IC50 value of 3.6 nM. CDK6/PIM1-IN-1 can significantly inhibit the proliferation of acute myeloid leukemia (AML) cells, arrest the cell cycle in G1 phase and induce cell apoptosis. CDK6/PIM1-IN-1 showed anti-AML activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | CDK6/PIM1-IN-1 is a balanced, potent, dual CDK6 (IC50: 39 nM) and PIM1 (IC50: 88 nM) inhibitor. CDK6/PIM1-IN-1 showed inhibitory effect on CDK4 with IC50 value of 3.6 nM. CDK6/PIM1-IN-1 can significantly inhibit the proliferation of acute myeloid leukemia (AML) cells, arrest the cell cycle in G1 phase and induce cell apoptosis. CDK6/PIM1-IN-1 showed anti-AML activity. |
Molecular Weight | 473.55 |
Formula | C25H28FN9 |
CAS No. | 2677026-14-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CDK6/PIM1-IN-1 2677026-14-9 inhibitor inhibit