IL-T3 Protein, Human, Recombinant (His)

Name: IL-T3 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-04650
Price: 63 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: LIR-5, LIR5, leukocyte immunoglobulin like receptor B4, ILT-3, ILT3, CD85K) Copy Product Info

Synonyms: LIR-5, LIR5, leukocyte immunoglobulin like receptor B4, ILT-3, ILT3, CD85K

Catalog No. TMPY-04650 Copy Product Info

IL-T3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is Q8NHJ6.

Pack Size	Price	USA Stock	Global Stock
5 µg	$63	-	In Stock
10 µg	$100	-	In Stock
20 µg	$163	-	In Stock
50 µg	$320	-	In Stock
100 µg	$567	7-10 days	7-10 days
200 µg	$1,000	7-10 days	7-10 days
500 µg	$2,120	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:SEC-HPLC: 99.0%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	Loaded Human ILT3 alpha Protein, His Tag on AR2G Biosensor, can bind Rhesus Angiopoietin-like 7 Protein, His Tag with an affinity constant of 68.94nM as determined in BLI assay (Routinely tested).
Description	IL-T3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is Q8NHJ6.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q8NHJ6
Construction	A DNA sequence encoding the human LILRB4 (NP_001265357.2) (Met1-Glu259) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Gln 22
Protein Purity	≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. ,
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	LIR-5, LIR5, leukocyte immunoglobulin like receptor B4, ILT-3, ILT3, CD85K
Research Background	LILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a Protein Coding gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1. LILRB4 is associated with the pathological processes of various inflammatory diseases. The LILRB4 is a central inhibitory receptor in Uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface.

Chemical Properties

Molecular Weight

27.7 kDa (predicted); 35-42 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.