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(R)-(-)-Niguldipine

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Catalog No. T23225

(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist.

(R)-(-)-Niguldipine
Other Forms of (R)-(-)-Niguldipine:

(R)-(-)-Niguldipine

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Catalog No. T23225
(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist.
Pack SizePriceAvailabilityQuantity
10 mg$3634-6 weeks
50 mg$1,8004-6 weeks
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Product Introduction

Bioactivity
Description
(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist.
Chemical Properties
Molecular Weight361.45
FormulaC21H23N5O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 10 mM, Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.7666 mL13.8332 mL27.6663 mL138.3317 mL
5 mM0.5533 mL2.7666 mL5.5333 mL27.6663 mL
10 mM0.2767 mL1.3833 mL2.7666 mL13.8332 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Niguldipine Hydrochloride(R)()Niguldipine hydrochloride(R) ( ) Niguldipine hydrochloride
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