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Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) (Synonyms: S6 Ribosomal Protein (p-Ser240, 244)...)

Name: Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516)
Brand: TargetMol
SKU: TMAY-01576
Rating: 4.5 (1 reviews)

Catalog No. TMAY-01576 Copy Product Info

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Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) is a Rabbit antibody targeting Phospho-S6 Ribosomal Protein (Ser240, 244). Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) can be used in IHC-P,WB.

Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516)

Copy Product Info

🥰Excellent

Catalog No. TMAY-01576

Synonyms S6 Ribosomal Protein (p-Ser240, 244), S6 Ribosomal Protein (p-S240, 244), S6, p-S6 Ribosomal Protein (Ser240, 244), p-S6 Ribosomal Protein (S240, 244), Phospho-S6 Ribosomal Protein (S240, 244), OK/SW-cl.2, eS6

Anti-Phospho-S6 Ribosomal Protein
(Ser240, 244) Antibody
(9Q516)

Pack Size	Price	USA Stock	Global Stock	Quantity
20 μL	$82	7-10 days	7-10 days
100 μL	$233	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) is a Rabbit antibody targeting Phospho-S6 Ribosomal Protein (Ser240, 244). Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) can be used in IHC-P,WB.
Synonyms	S6 Ribosomal Protein (p-Ser240, 244), S6 Ribosomal Protein (p-S240, 244), S6, p-S6 Ribosomal Protein (Ser240, 244), p-S6 Ribosomal Protein (S240, 244), Phospho-S6 Ribosomal Protein (S240, 244), OK/SW-cl.2, eS6
Ig Type	Rabbit IgG
Clone	9Q516
Reactivity	Human; Species predicted to react based on 100% sequence homology: Mouse
Specificity	Human Species predicted to react based on 100% sequence homology: Mouse
Verified Activity	1. Western blot analysis of extracts from serum-starved HEK293, untreated (-) or treated with 20% FBS, using Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody, Rabbit MAb (upper), or Anti-RPS6 Antibody, Rabbit Polyclonal (lower) at 1:1000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human carcinoma of sigmoid tissue,untreated (left) or lambda phosphatase-treated (right), using Recombinant Phospho-S6 Ribosomal Protein (Ser240/244) Antibody, Rabbit Monoclonal at 1:2000 dilution. 3. Western blot analysis of extracts from serum-starved HEK293, treated with 20% FBS (30 min), using Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody, Rabbit MAb at dilution of 1:1000, 1:5000 and 1:25000. (Validation Experiment) 4. Western blot analysis of extracts from serum-starved HEK293, untreated (line A); treated with FBS(20%, 30min) (line B); treated with FBS and λ-phosphatase (line C) using Phospho-S6 Ribosomal Protein (Ser240, 244) rabbit monoclonal Antibody at 1:5000 dilution. (Validation Experiment) 5. Western blot analysis of extracts from serum-starved , untreated (line A); treated with FBS(20%, 30min), without peptide (line B) or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-S6 Ribosomal Protein (Ser240, 244) rabbit monoclonal Antibody at 1:5000 dilution. (Validation Experiment)
Application	IHC-P WB
Recommended Dose	WB: 1:1000-1:5000; IHC-P: 1:1000-1:5000
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	The antibody is produced by immunizing rabbits with a synthetic phosphopeptide corresponding to residues around (Ser240, 244) of Human Phospho-S6 Ribosomal Protein.
Purification	Protein A
Appearance	Liquid
Formulation	10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
Research Background	Ribosomal protein S6 (rpS6), a component of the 40S ribosomal subunit, is involved in multiple cellular bioactivities. RPS6 is a downstream substrate of PI3K/Akt/mTOR/ kinase and MAPK kinase pathways and its dephosphorylation is also triggered by DNA double-strand breaks. The ribosomal protein S6 (RPS6) is a downstream component of the signaling mediated by the target of rapamycin (TOR) kinase that acts as a central regulator of the key metabolic processes, such as protein translation and ribosome biogenesis, in response to various environmental cues. mTORC1/rpS6 signaling complex promoted Sertoli blood-testis barrier (BTB) remodeling by perturbing Sertoli cell-cell adhesion site known as the basal ectoplasmic specialization (ES). mTORC1/rpS6 complex also promoted disruption of spermatid adhesion at the Sertoli-spermatid interface called the apical ES.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	A synthetic peptide corresponding to residues around (Ser240, 244) of Human Phospho-S6 Ribosomal Protein.
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

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