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Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) is a Mouse antibody targeting UMP-CMP kinase/CMPK1. Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) is a Mouse antibody targeting UMP-CMP kinase/CMPK1. Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) can be used in WB. |
Alias | UMPK, UMP-CMPK, UMK, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic, CMPK, CMK, CK |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 1T371 |
Reactivity | Human |
Verified Activity | Anti-CMPK1 mouse monoclonal antibody at 1:500 dilution. -Lane A: K562 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:22 kDa. -Observed band size:22 kDa |
Application | WB |
Recommended Dose | WB: 1:500-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CMPK1 (rh CMPK1; TMPY-04480; P30085; Met1-Gly196). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human CMPK1 Protein (TMPY-04480) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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