PRNP/Prion Protein Protein, Human, Recombinant (hFc)

Catalog No. TMPY-03842 Copy Product Info

PRNP/Prion Protein Protein, Human, Recombinant (hFc) is expressed in E. coli expression system with His tag. The predicted molecular weight is 49.4 kDa and the accession number is P04156.

PRNP/Prion Protein Protein, Human, Recombinant (hFc)

Catalog No. TMPY-03842

Copy Product Info

PRNP/Prion Protein Protein, Human, Recombinant (hFc) is expressed in E. coli expression system with His tag. The predicted molecular weight is 49.4 kDa and the accession number is P04156.

Pack Size	Price	USA Stock	Global Stock
5 μg	$79	7-10 days	7-10 days
10 μg	$129	7-10 days	7-10 days
20 μg	$208	7-10 days	7-10 days
50 μg	$419	7-10 days	7-10 days
100 μg	$812	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Information

Biological Activity	Immobilized Human PRNP, hFc Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-PRNP Antibody, hFc Tag with the EC50 of 33.2 ng/ml determined by ELISA.
Description	PRNP/Prion Protein Protein, Human, Recombinant (hFc) is expressed in E. coli expression system with His tag. The predicted molecular weight is 49.4 kDa and the accession number is P04156.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P04156
Synonyms	PrPc,PrP33-35C,PrP27-30,PrP,PRIP,prion protein,p27-30,KURU,GSS,CJD,CD230,ASCR,AltPrP
Construction	Lys23-Ser230
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	49.4 kDa (Predicted); 60-67 kDa (Due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Prion protein gene (PRNP) variants determine the susceptibility of humans, sheep and mice to prion diseases, whereas polymorphisms in the open reading frame (ORF) of bovine PRNP seem to be unrelated to the incidence of bovine spongiform encephalopathy (BSE). According to the latest reports, the genetic susceptibility of cattle to BSE is associated with polymorphisms ofthe regulatory region of the PRNP gene and the level ofits expression.