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HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)

Catalog No. TMPJ-00899
Synonyms: HER3, Proto-oncogene-like protein c-ErbB-3, ERBB3, Tyrosine kinase-type cell surface receptor HER3

HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 116.00
50 μg 5 days $ 310.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3.
Species Human
Expression System HEK293 Cells
Tag C-hFc
Accession Number P21860-3
Synonyms HER3, Proto-oncogene-like protein c-ErbB-3, ERBB3, Tyrosine kinase-type cell surface receptor HER3
Amino Acid Ser20-Phe331
Construction Ser20-Phe331
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 65 KDa (reducing condition)
Endotoxin < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belongs to the protein kinase superfamily,tyr protein kinase family and EGF receptor subfamily.It contains 1 protein kinase domain and it is expressed in Epithelial tissues and brain. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity.

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Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) HER3 ERBB-3 Proto-oncogene-like protein c-ErbB-3 HER 3 HER-3 ERBB 3 ERBB3 Tyrosine kinase-type cell surface receptor HER3 recombinant recombinant-proteins proteins protein

 

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