Siglec-3/CD33 Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00844 Copy Product Info

Siglec-3/CD33 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.6 kDa and the accession number is P20138-1.

Siglec-3/CD33 Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00844

Copy Product Info

Siglec-3/CD33 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.6 kDa and the accession number is P20138-1.

Pack Size	Price	USA Stock	Global Stock
5 μg	$46	7-10 days	7-10 days
10 μg	$72	7-10 days	7-10 days
20 μg	$115	7-10 days	7-10 days
50 μg	$222	7-10 days	7-10 days
100 μg	$371	7-10 days	7-10 days
200 μg	$673	7-10 days	7-10 days
500 μg	$1,490	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Information

Biological Activity	Immobilized Human Siglec-3, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-Siglec-3 Antibody, hFc Tag with the EC50 of 3.1ng/ml determined by ELISA.
Description	Siglec-3/CD33 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.6 kDa and the accession number is P20138-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	P20138-1
Synonyms	Siglec-3,Siglec3,p67,gp67,FLJ00391,CD33 molecule,CD33
Construction	Asp18-His259
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	29.6 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 20 mM PB, 500 mM NaCl (pH 8.0).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.