Siglec-3/CD33 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.6 kDa and the accession number is P20138-1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 371.00 | |
500 μg | 5 days | $ 1,490.00 | |
1 mg | 5 days | $ 2,480.00 |
Description | Siglec-3/CD33 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.6 kDa and the accession number is P20138-1. |
Species | Human |
Expression System | HEK293 Cells |
Tag | C-His-Avi |
Accession Number | P20138-1 |
Synonyms | p67, CD33 molecule, FLJ00391, Siglec3, Siglec-3, gp67, CD33 |
Construction | Asp18-His259 |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | 29.6 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in 20 mM PB, 500 mM NaCl (pH 8.0). |
Stability & Storage |
It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs. |
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Siglec-3/CD33 Protein, Human, Recombinant (His & Avi) CD 33 p67 CD33 molecule FLJ 00391 FLJ-00391 FLJ00391 Siglec3 Siglec-3 gp67 CD-33 CD33 recombinant recombinant-proteins proteins protein