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1-Ethynylnaphthalene

Name: 1-Ethynylnaphthalene
Brand: TargetMol
SKU: T7427
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7427Cas No. 15727-65-8

1-Ethynylnaphthalene [1-EN] is a selective inhibitor of cytochrome P450 IB1 (CYP1B1).

1-Ethynylnaphthalene

🥰Excellent

Purity: 99.05%

Catalog No. T7427Cas No. 15727-65-8

1-Ethynylnaphthalene [1-EN] is a selective inhibitor of cytochrome P450 IB1 (CYP1B1).

Pack Size	Price	Availability	Quantity
1 g	$35	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.05%

Resource Download

COA HNMR GC HPLC

Product Introduction

Bioactivity

Description

1-Ethynylnaphthalene [1-EN] is a selective inhibitor of cytochrome P450 IB1 (CYP1B1).

Chemical Properties

Molecular Weight	152.19
Formula	C₁₂H₈
Cas No.	15727-65-8
Smiles	C#Cc1cccc2ccccc12
Relative Density.	1.070g/mLat 25°C(lit.)
Color	Red
Appearance	Liquid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (394.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.5707 mL	32.8537 mL	65.7073 mL	328.5367 mL
5 mM	1.3141 mL	6.5707 mL	13.1415 mL	65.7073 mL
10 mM	0.6571 mL	3.2854 mL	6.5707 mL	32.8537 mL
20 mM	0.3285 mL	1.6427 mL	3.2854 mL	16.4268 mL
50 mM	0.1314 mL	0.6571 mL	1.3141 mL	6.5707 mL
100 mM	0.0657 mL	0.3285 mL	0.6571 mL	3.2854 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc