Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Opc 8490

🥰Excellent
Catalog No. T33807Cas No. 123941-50-4
Alias Opc-8490, Opc8490

Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator that increases Ca current (ICa) in a dose-dependent and reversible manner and prolongs atrial action potential in a concentration-dependent manner.

Opc 8490

Opc 8490

🥰Excellent
Purity: 98.88%
Catalog No. T33807Alias Opc-8490, Opc8490Cas No. 123941-50-4
Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator that increases Ca current (ICa) in a dose-dependent and reversible manner and prolongs atrial action potential in a concentration-dependent manner.
Pack SizePriceAvailabilityQuantity
1 mg$219In Stock
5 mg$548In Stock
10 mg$792In Stock
25 mg$1,220In Stock
50 mg$1,980In Stock
Add to Cart
Add to Quotation
Bulk & Custom
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
Questions
View More

Batch Information

Select Batch
Purity:98.88%
Contact us for more batch information

Resource Download

Product Introduction

Bioactivity
Description
Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator that increases Ca current (ICa) in a dose-dependent and reversible manner and prolongs atrial action potential in a concentration-dependent manner.
In vivo
Opc 8490 (0.1, 0.3, and 1 μM/kg) induced a dose-dependent decrease in heart rate and arterial blood pressure in intact assisted dogs when administered intravenously; Opc 8490 (1 μM) induced a triphasic effect, Ph1 followed by Ph2 and a slightly positive (Ph3) chronotropic and inotropic effect.[3]
AliasOpc-8490, Opc8490
Chemical Properties
Molecular Weight597.61
FormulaC30H35N3O10
Cas No.123941-50-4
SmilesO=C(O)CC(O)(C(=O)O)CC(=O)O.O=C(C1=CC=C2NC(=O)CCC2=C1)N3CCN(CC3)CCCC(=O)C=4C=CC=CC4
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Opc 8490 | purchase Opc 8490 | Opc 8490 cost | order Opc 8490 | Opc 8490 chemical structure | Opc 8490 in vivo | Opc 8490 formula | Opc 8490 molecular weight