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Anti-ACACA Antibody (3I598)
😃Good
Catalog No. TMAB-00029
Alias Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC
Anti-ACACA Antibody (3I598) is a Rabbit antibody targeting ACACA. Anti-ACACA Antibody (3I598) can be used in IF,IHC-Fr,WB.
Anti-ACACA Antibody (3I598)
Anti-ACACA Antibody (3I598)
😃Good
Catalog No. TMAB-00029Alias Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC
Anti-ACACA Antibody (3I598) is a Rabbit antibody targeting ACACA. Anti-ACACA Antibody (3I598) can be used in IF,IHC-Fr,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $153 | 7-10 days | 7-10 days | |
| 50 μL | $271 | 7-10 days | 7-10 days | |
| 100 μL | $489 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-ACACA Antibody (3I598) is a Rabbit antibody targeting ACACA. Anti-ACACA Antibody (3I598) can be used in IF,IHC-Fr,WB. |
| Synonyms | Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC |
| Ig Type | IgG |
| Clone | 3I598 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | Sample: Lane 1: Mouse Brain Lysates Lane 2: Human K562 cell Lysates Primary: Anti-Acetyl CoA Carboxylase 1 (ACC1) (TMAB-00029) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 265 kDa Observed band size: 265 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human Acetyl CoA Carboxylase 1(ACC1) |
| Antigen Species | Human |
| Gene Name | ACACA |
| Gene ID | |
| Protein Name | Acetyl-CoA carboxylase 1 |
| Uniprot ID | |
| Biology Area | Integration of energy metabolism,Metabolism of lipids and lipoproteins,Synthesis,Integration of energy,Lipid metabolism,Mitochondrial markers,Fatty acid oxidation,Lipid metabolism,Mitochondrial |
| Function | Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. |
| Molecular Weight | Theoretical: 265 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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