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Anti-ACACA Antibody (3I598) (Synonyms: Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase ...)

Catalog No. TMAB-00029 Copy Product Info
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Anti-ACACA Antibody (3I598) is a Rabbit antibody targeting ACACA. Anti-ACACA Antibody (3I598) can be used in IF,IHC-Fr,WB.

Anti-ACACA Antibody (3I598)

Copy Product Info
🥰Excellent
Catalog No. TMAB-00029
Synonyms Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC

Anti-ACACA Antibody (3I598) is a Rabbit antibody targeting ACACA. Anti-ACACA Antibody (3I598) can be used in IF,IHC-Fr,WB.

Anti-ACACA Antibody
(3I598)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1537-10 days7-10 days
50 μL$2717-10 days7-10 days
100 μL$4897-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ACACA Antibody (3I598) is a Rabbit antibody targeting ACACA. Anti-ACACA Antibody (3I598) can be used in IF,IHC-Fr,WB.
SynonymsAcetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC
Ig Type
IgG
Clone
3I598
Reactivity
Human,Mouse,Rat
Verified Activity
Sample:
Lane 1: Mouse Brain Lysates
Lane 2: Human K562 cell Lysates
Primary: Anti-Acetyl CoA Carboxylase 1 (ACC1) (TMAB-00029) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 265 kDa
Observed band size: 265 kDa
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC-Fr: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificityExpressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundAcetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Acetyl CoA Carboxylase 1(ACC1)
Antigen Species
Human
Gene Name
ACACA
Gene ID
Protein Name
Acetyl-CoA carboxylase 1
Uniprot ID
Biology Area
Integration of energy metabolism,Metabolism of lipids and lipoproteins,Synthesis,Integration of energy,Lipid metabolism,Mitochondrial markers,Fatty acid oxidation,Lipid metabolism,Mitochondrial
Function
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Chemical Properties
Molecular WeightTheoretical: 265 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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