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Anti-Cathelicidin/Camp Polyclonal Antibody (Synonyms: LL37, LL 37, HSD26, hCAP-18, FALL-39 peptide antibioti...)
Catalog No. TMAB-00296 Copy Product Info
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Anti-Cathelicidin/Camp Polyclonal Antibody is a Rabbit antibody targeting Cathelicidin/Camp. Anti-Cathelicidin/Camp Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P.
Anti-Cathelicidin/Camp Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00296
Synonyms LL37, LL 37, HSD26, hCAP-18, FALL-39 peptide antibiotic, FALL39, CRAMP, Cathelicidin antimicrobial peptide, CAP-18, CAP18, CAMP, Antibacterial peptide RK-31, Antibacterial peptide LL-37, Antibacterial peptide LL-29, Antibacterial peptide LL-23, Antibacterial peptide KS-30, Antibacterial peptide KR-20, Antibacterial peptide FF-33;, Antibacterial peptide FALL-39, 8 kDa cationic antimicrobial protein
Anti-Cathelicidin/Camp Polyclonal Antibody is a Rabbit antibody targeting Cathelicidin/Camp. Anti-Cathelicidin/Camp Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P.
Anti-Cathelicidin/Camp Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Cathelicidin/Camp Polyclonal Antibody is a Rabbit antibody targeting Cathelicidin/Camp. Anti-Cathelicidin/Camp Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P. |
| Synonyms | LL37, LL 37, HSD26, hCAP-18, FALL-39 peptide antibiotic, FALL39, CRAMP, Cathelicidin antimicrobial peptide, CAP-18, CAP18, CAMP, Antibacterial peptide RK-31, Antibacterial peptide LL-37, Antibacterial peptide LL-29, Antibacterial peptide LL-23, Antibacterial peptide KS-30, Antibacterial peptide KR-20, Antibacterial peptide FF-33;, Antibacterial peptide FALL-39, 8 kDa cationic antimicrobial protein |
| Ig Type | IgG |
| Reactivity | (predicted:Mouse,Rat) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed in bone marrow and testis and neutrophils. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils. Along with the family of proteins known as defensins, cathelicidins participate in the first line of defense by preventing local infection and systemic invasion of microbes. FALL-39 precursor (FALL-39 peptide antibiotic, cationic anti-microbial protein, CAMP, CAP-18, HSD26) is a cathelicidin anti-microbial protein that contains the antibacterial peptide LL-37 (amino acids 134-170). In contrast to the defensins, which are cysteine-rich peptides that fold in ∫-pleated sheets, LL-37 is a cysteine-free peptide that can adopt an amphipathic å-helical conformation. LL-37 binds to bacterial lipopolysaccharides (LPS) and is a potent chemotactic factor for recruiting mast cells to sites of inflammation. LL-37 is present in inflammatory skin diseases that include psoriasis, sub-acute lupus erthematosus, dermatitis and nickel contact hypersensitivity. It is not found in normal skin epidermis. The secreted protein is expressed primarily in bone marrow, testis and neutrophils. The mouse and rat ortholog, CRAMP (cathelin-related antimicrobial peptide), is also part of the cathelicidin family of host defense peptides. These include precursors of potent antimicrobial peptides that direct antimicrobial activity against various microbial pathogens and also activate mesenchymal cells during wound repair. CRAMP is expressed in testis, spleen, stomach and intestine. This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The protein plays an important role in innate immunity defense against viruses. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2021] |
| Immunogen | KLH conjugated synthetic peptide: mouse Camp |
| Antigen Species | Mouse |
| Gene Name | Camp |
| Gene ID | |
| Protein Name | Cathelicidin antimicrobial peptide |
| Uniprot ID | |
| Biology Area | cAMP |
| Function | Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. |
| Molecular Weight | Theoretical: 19 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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