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Anti-Cathelicidin/Camp Polyclonal Antibody
😃Good
Catalog No. TMAB-00296
Alias LL37, LL 37, HSD26, hCAP-18, FALL-39 peptide antibiotic, FALL39, CRAMP, Cathelicidin antimicrobial peptide, CAP-18, CAP18, CAMP, Antibacterial peptide RK-31, Antibacterial peptide LL-37, Antibacterial peptide LL-29, Antibacterial peptide LL-23, Antibacterial peptide KS-30, Antibacterial peptide KR-20, Antibacterial peptide FF-33;, Antibacterial peptide FALL-39, 8 kDa cationic antimicrobial protein
Anti-Cathelicidin/Camp Polyclonal Antibody is a Rabbit antibody targeting Cathelicidin/Camp. Anti-Cathelicidin/Camp Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Anti-Cathelicidin/Camp Polyclonal Antibody
Anti-Cathelicidin/Camp Polyclonal Antibody
😃Good
Catalog No. TMAB-00296Alias LL37, LL 37, HSD26, hCAP-18, FALL-39 peptide antibiotic, FALL39, CRAMP, Cathelicidin antimicrobial peptide, CAP-18, CAP18, CAMP, Antibacterial peptide RK-31, Antibacterial peptide LL-37, Antibacterial peptide LL-29, Antibacterial peptide LL-23, Antibacterial peptide KS-30, Antibacterial peptide KR-20, Antibacterial peptide FF-33;, Antibacterial peptide FALL-39, 8 kDa cationic antimicrobial protein
Anti-Cathelicidin/Camp Polyclonal Antibody is a Rabbit antibody targeting Cathelicidin/Camp. Anti-Cathelicidin/Camp Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Cathelicidin/Camp Polyclonal Antibody is a Rabbit antibody targeting Cathelicidin/Camp. Anti-Cathelicidin/Camp Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA. |
| Alias | LL37, LL 37, HSD26, hCAP-18, FALL-39 peptide antibiotic, FALL39, CRAMP, Cathelicidin antimicrobial peptide, CAP-18, CAP18, CAMP, Antibacterial peptide RK-31, Antibacterial peptide LL-37, Antibacterial peptide LL-29, Antibacterial peptide LL-23, Antibacterial peptide KS-30, Antibacterial peptide KR-20, Antibacterial peptide FF-33;, Antibacterial peptide FALL-39, 8 kDa cationic antimicrobial protein |
| Ig Type | IgG |
| Reactivity | (predicted:Mouse,Rat) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils. Along with the family of proteins known as defensins, cathelicidins participate in the first line of defense by preventing local infection and systemic invasion of microbes. FALL-39 precursor (FALL-39 peptide antibiotic, cationic anti-microbial protein, CAMP, CAP-18, HSD26) is a cathelicidin anti-microbial protein that contains the antibacterial peptide LL-37 (amino acids 134-170). In contrast to the defensins, which are cysteine-rich peptides that fold in ∫-pleated sheets, LL-37 is a cysteine-free peptide that can adopt an amphipathic å-helical conformation. LL-37 binds to bacterial lipopolysaccharides (LPS) and is a potent chemotactic factor for recruiting mast cells to sites of inflammation. LL-37 is present in inflammatory skin diseases that include psoriasis, sub-acute lupus erthematosus, dermatitis and nickel contact hypersensitivity. It is not found in normal skin epidermis. The secreted protein is expressed primarily in bone marrow, testis and neutrophils. The mouse and rat ortholog, CRAMP (cathelin-related antimicrobial peptide), is also part of the cathelicidin family of host defense peptides. These include precursors of potent antimicrobial peptides that direct antimicrobial activity against various microbial pathogens and also activate mesenchymal cells during wound repair. CRAMP is expressed in testis, spleen, stomach and intestine. This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The protein plays an important role in innate immunity defense against viruses. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2021] |
| Immunogen | KLH conjugated synthetic peptide: mouse Camp |
| Antigen Species | Mouse |
| Gene ID | |
| Uniprot ID | |
| Biology Area | cAMP |
| Molecular Weight | Theoretical: 19 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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