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Palmitoyl thio-PC

Catalog No. T37244 CAS 113881-60-0

Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Palmitoyl thio-PC is a chromogenic PLA2 substrate that contains a palmitoyl thioester at the sn-2 position of the glycerol backbone. Hydrolysis of the thioester by PLA2 yields a free thiol that reacts readily with DTNB (Ellman's reagent) giving a bright yellow product with an absorbance maximum at 412 nm. Palmitoyl thio-PC has been used to measure bee venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system.

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Palmitoyl thio-PC, CAS 113881-60-0

Pack Size	Availability	Price/USD
1 mg	35 days	$ 283.00
5 mg	35 days	$ 1,250.00
10 mg	35 days	$ 2,230.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	750.11
Formula	C40H80NO7PS
CAS No.	113881-60-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 50 mg/mL

Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/mL

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Palmitoyl thio-PC 113881-60-0 Palmitoyl thio PC Palmitoyl thioPC inhibitor inhibit

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