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SMARCA-BD ligand 1 for Protac dihydrochloride

🥰Excellent
Catalog No. T13890Cas No. 2369053-68-7

SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunit SMARCA2 and is used for degrading SMARCA2 based on PROTAC.

SMARCA-BD ligand 1 for Protac dihydrochloride
Other Forms of SMARCA-BD ligand 1 for Protac dihydrochloride:

SMARCA-BD ligand 1 for Protac dihydrochloride

🥰Excellent
Purity: 99.01%
Catalog No. T13890Cas No. 2369053-68-7
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunit SMARCA2 and is used for degrading SMARCA2 based on PROTAC.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$37-In Stock
5 mg$88-In Stock
10 mg$143-In Stock
25 mg$238-In Stock
50 mg$341-In Stock
100 mg$467-In Stock
200 mg$647-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.01%
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Product Introduction

Bioactivity
Description
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunit SMARCA2 and is used for degrading SMARCA2 based on PROTAC.
Chemical Properties
Molecular Weight344.24
FormulaC14H19Cl2N5O
Cas No.2369053-68-7
SmilesCl.Cl.Nc1nnc(cc1N1CCNCC1)-c1ccccc1O
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 2.4 mg/mL (7.1 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9050 mL14.5248 mL29.0495 mL145.2475 mL
5 mM0.5810 mL2.9050 mL5.8099 mL29.0495 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

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