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PEN (human) aceate

🥰Excellent
Catalog No. TP1949L

PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.

PEN (human) aceate
Other Forms of PEN (human) aceate:

PEN (human) aceate

🥰Excellent
Purity: 99.25%
Catalog No. TP1949L
PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$148-In Stock
5 mg$336-In Stock
10 mg$497-In Stock
25 mg$898-In Stock
50 mg$1,362-In Stock
100 mg$1,997-In Stock
200 mg$2,994-In Stock
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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]
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Purity:99.25%
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Product Introduction

Bioactivity
Description
PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.
In vitro
Mouse PEN (mPEN) and rat PEN (rPEN) only differ by one residue at the N-terminal end, whereas human PEN (hPEN) is more divergent and has the sequence PEG instead of PEN[2].
PEN binds and activates a GPCR in the brain[2].
Chemical Properties
Molecular Weight2275.51
FormulaC99H163N27O34
SmilesCC(O)=O.CC(C)[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC(CNC([C@H](CC(C)C)NC([C@H](C(C)C)NC(CNC([C@H](CCC(O)=O)NC([C@H]1N(C([C@H]2N(C([C@H](CC(C)C)NC([C@H](CCC(O)=O)NC([C@H](CO)NC(CNC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](CC3=CNC=N3)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC2)=O)CCC1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
SequenceH-Ala-Ala-Asp-His-Asp-Val-Gly-Ser-Glu-Leu-Pro-Pro-Glu-Gly-Val-Leu-Gly-Ala-Leu-Leu-Arg-Val-OH
Sequence ShortAADHDVGSELPPEGVLGALLRV
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

PEN (human) aceatePEN aceateGPCR19
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