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Prostaglandin I3 (sodium salt)

Name: Prostaglandin I3 (sodium salt)
Brand: TargetMol
SKU: T36546
Rating: 4.5 (1 reviews)

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Catalog No. T36546Cas No. 68324-96-9

Alias Prostaglandin I3 (sodium salt)

PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.

Prostaglandin I3 (sodium salt)

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Catalog No. T36546Alias Prostaglandin I3 (sodium salt)Cas No. 68324-96-9

Pack Size	Price	USA Warehouse	Global Warehouse
50 μg	$352	35 days	35 days
100 μg	$667	35 days	35 days
500 μg	$2,780	35 days	35 days
1 mg	$3,500	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.
Synonyms	Prostaglandin I3 (sodium salt)

Chemical Properties

Molecular Weight	372.43
Formula	C₂₀H₂₉NaO₅
Cas No.	68324-96-9
Smiles	[Na].[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)C\C=C/CC)[C@@]1([H])C\C(O2)=C\CCCC(O)=OjcExt:v:0:0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH >10.2): 10 mg/mL (26.85 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH >10.2)

	1mg	5mg	10mg	50mg
1 mM	2.6851 mL	13.4253 mL	26.8507 mL	134.2534 mL
5 mM	0.5370 mL	2.6851 mL	5.3701 mL	26.8507 mL
10 mM	0.2685 mL	1.3425 mL	2.6851 mL	13.4253 mL
20 mM	0.1343 mL	0.6713 mL	1.3425 mL	6.7127 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Prostaglandin I-3 (sodium salt)Prostaglandin I3

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