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Anti-Complement factor H/CFH Antibody (2X509) (Synonyms: HUS, HF2, HF1, HF, H factor 1, FHL1, FH, Complem...)

Catalog No. TMAC-01422 Copy Product Info
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Anti-Complement factor H/CFH Antibody (2X509) is a Rabbit antibody targeting Complement factor H/CFH. Anti-Complement factor H/CFH Antibody (2X509) can be used in ICC,WB.

Anti-Complement factor H/CFH Antibody (2X509)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01422
Synonyms HUS, HF2, HF1, HF, H factor 1, FHL1, FH, Complement factor H, CFHL3, CFH, ARMS1, ARMD4, AMBP1, AHUS1

Anti-Complement factor H/CFH Antibody (2X509) is a Rabbit antibody targeting Complement factor H/CFH. Anti-Complement factor H/CFH Antibody (2X509) can be used in ICC,WB.

Anti-Complement factor H/CFH Antibody
(2X509)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Complement factor H/CFH Antibody (2X509) is a Rabbit antibody targeting Complement factor H/CFH. Anti-Complement factor H/CFH Antibody (2X509) can be used in ICC,WB.
SynonymsHUS, HF2, HF1, HF, H factor 1, FHL1, FH, Complement factor H, CFHL3, CFH, ARMS1, ARMD4, AMBP1, AHUS1
Ig Type
IgG
Clone
2X509
Reactivity
Human
Verified Activity
1. Western blot analysis of Factor H on human lung tissue lysate using anti-Factor H antibody at 1/1,000 dilution.
2. ICC staining Factor H in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Factor H in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe Factor H gene family is a multidomain, multifunctional protein family whose individual members are defined by conserved structural elements, which display diverse yet often overlapping functions. These proteins share a common structural motif, the short consensus repeat (SCR), which is structurally conserved among related genes and between phylogenetically divergent species. The human complement Factor H (FH, CFH, HUS, b-1H) gene encodes a 1213 amino acid serum glycoprotein which is arranged into 20 SCRs, each approximately 60 amino acids long, and an 18-residue leader sequence. Factor H controls the function of the alternative complement pathway and acts as a cofactor with Factor I (C3b inactivator). In addition, Factor H has functional activity outside of the complement system, where it can bind to the cellular integrin receptor (CD11b/CD18), interact with cell surface glycosaminoglycans and associate with the surface of certain pathogenic microorganisms. Deficiencies in Factor H is a common characteristic of acute renal disease.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 140 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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