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Kell Protein, Human, Recombinant (His)

(Synonyms: Kell blood group glycoprotein, KEL, CD238) Copy Product Info

Synonyms: Kell blood group glycoprotein, KEL, CD238

Catalog No. TMPJ-00902 Copy Product Info
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.
Kell Protein, Human, Recombinant (His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$80-In Stock
10 µg$129-In Stock
20 µg$198-In Stock
50 µg$417-In Stock
100 µg$6686-8 weeks6-8 weeks
200 µg$1,0706-8 weeks6-8 weeks
500 µg$1,9006-8 weeks6-8 weeks
1 mg$2,7306-8 weeks6-8 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 95% as determined by reducing SDS-PAGE.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.
Species
Human
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberP23276
Amino AcidAsn68-Trp732
ConstructionAsn68-Trp732
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
SynonymsKell blood group glycoprotein, KEL, CD238
Research Background
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.
Chemical Properties
Molecular Weight85-120 KDa (reducing condition)
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Kell Protein, Human, Recombinant (His) chemical structure | Kell Protein, Human, Recombinant (His) molecular weight