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Anti-IL-18R beta/IL-18RAP Antibody (7V221)
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Catalog No. TMAY-03892
Alias interleukin 18 receptor accessory protein, IL-18R β/IL-18RAP
Anti-IL-18R beta/IL-18RAP Antibody (7V221) is a Mouse antibody targeting IL-18R beta/IL-18RAP. Anti-IL-18R beta/IL-18RAP Antibody (7V221) can be used in ELISA.
Anti-IL-18R beta/IL-18RAP Antibody (7V221)
Anti-IL-18R beta/IL-18RAP Antibody (7V221)
😃Good
Catalog No. TMAY-03892Alias interleukin 18 receptor accessory protein, IL-18R β/IL-18RAP
Anti-IL-18R beta/IL-18RAP Antibody (7V221) is a Mouse antibody targeting IL-18R beta/IL-18RAP. Anti-IL-18R beta/IL-18RAP Antibody (7V221) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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| Description | Anti-IL-18R beta/IL-18RAP Antibody (7V221) is a Mouse antibody targeting IL-18R beta/IL-18RAP. Anti-IL-18R beta/IL-18RAP Antibody (7V221) can be used in ELISA. |
| Alias | interleukin 18 receptor accessory protein, IL-18R β/IL-18RAP |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 7V221 |
| Reactivity | Rhesus |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rhesus IL18RAP (TMPY-03103; XP_001108108.1; Met1-Arg356). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand-binding subunit of the IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18. IL18RAP is required for the high-affinity binding of interleukin 18 (IL-18) to its receptor complex. IL18RAP together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. Two putative isoforms of IL18RAP were detected and the ratios and total levels of these isoforms may contribute to the etiology of coeliac disease. IL18R1 and IL18RAP polymorphisms have been found associated with diseases such as schizophrenia, HSV1 seropositivity, and atopic asthma. Analysis of IL18R1 and IL18RAP SNPs in 5 European prospective cohorts suggests that the variability of these genes are unlikely to contribute to modulate the risk of CVD in European populations. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Rhesus IL18RAP protein (TMPY-03103) |
| Antigen Species | Rhesus |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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