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C-Reactive Protein Protein, Human, Recombinant

(Synonyms: PTX1, C-reactive protein, pentraxin-related, C-Reactive Protein) Copy Product Info

Synonyms: PTX1, C-reactive protein, pentraxin-related, C-Reactive Protein

Catalog No. TMPY-03363 Copy Product Info
Purity: 98.3%
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1.
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$35-In Stock
20 µg$52-In Stock
50 µg$94-In Stock
100 µg$153-In Stock
200 µg$253-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.3%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1.
Species
Human
Expression System
HEK293 Cells
TagTag Free
Accession NumberP02741-1
ConstructionA DNA sequence encoding the human CRP (P02741-1) (Met1-Pro224) was expressed and purified. Predicted N terminal: Gln 19
Protein Purity
≥ 90 % as determined by SDS-PAGE ≥ 95 % as determined by SEC-HPLC.
C-Reactive Protein Protein, Human, Recombinant,C-Reactive Protein Protein, Human, Recombinant
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 0.2M NaCl, 5 mM CaCl2, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsPTX1, C-reactive protein, pentraxin-related, C-Reactive Protein
Research Background
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased CRP production and coronary atherothrombotic events is of particular interest.
Chemical Properties
Molecular Weight23 kDa (predicted); 26 kDa (reducing condition, due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: C-Reactive Protein Protein, Human, Recombinant chemical structure | C-Reactive Protein Protein, Human, Recombinant molecular weight