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Anti-QPRTase Polyclonal Antibody
(Synonyms: Quinolinate Phosphoribosyltransferase [Decarboxylating], QPRTase, QPRT, QAPRTase, Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating]) Copy Product Info
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Synonyms: Quinolinate Phosphoribosyltransferase [Decarboxylating], QPRTase, QPRT, QAPRTase, Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating]
Catalog No. TMAB-01599 Copy Product Info
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Anti-QPRTase Polyclonal Antibody is a Rabbit antibody targeting QPRTase. Anti-QPRTase Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-QPRTase Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-QPRTase Polyclonal Antibody is a Rabbit antibody targeting QPRTase. Anti-QPRTase Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Quinolinate Phosphoribosyltransferase [Decarboxylating], QPRTase, QPRT, QAPRTase, Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating] |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Cow,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Hexamer formed by 3 homodimers. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1 mg/mL |
| Research Background | Quinolinate phosphoribosyltransferase (QPRTase) is a major enzyme in the catabolism of quinolinate. Quinolinate is an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide, and pyrophosphate. Catabolism of quinolinate is vital due to the quinolinate’s neurotoxicity. Increased levels of quinolinate have been linked to neurodegenerative symptoms associated with meningitis and AIDS. QAPRTase has a seven-stranded alpha/beta-barrel domain which is similar in structure to the eight-stranded alpha/beta-barrel enzymes. The protein possesses a novel fold in comparison to other members of the PRTase family. This fold comprises a structure combining two domains. The structure is part alpha/beta barrel-like domain, and part alpha/beta N-terminal domain. |
| Immunogen | KLH conjugated synthetic peptide: human QPRT/QAPRTase |
| Antigen Species | Human |
| Gene Name | QPRT |
| Gene ID | |
| Protein Name | Nicotinate-nucleotide pyrophosphorylase [carboxylating] |
| Uniprot ID | |
| Biology Area | Amino acid metabolism,Neurodegenerative disease,Alzheimer's disease,Huntington's disease,Neurodegenerative disease,Amino Acids |
| Function | Involved in the catabolism of quinolinic acid (QA). |
| Molecular Weight | Theoretical: 31 kDa. Actual: 31 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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