store at low temperature
store at -80°C
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 238.00 | |
5 mg | In stock | $ 639.00 | |
10 mg | In stock | $ 891.00 | |
25 mg | In stock | $ 1,370.00 | |
50 mg | In stock | $ 1,830.00 | |
100 mg | In stock | $ 2,490.00 |
Description | Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH). |
In vitro | Impaired by Emapalumab (NI-0501) is the interaction between IFNcR1 and IFNc-Receptor-2 (IFNcR2) induced by IFNc at the cell surface. |
Synonyms | NI-0501 |
Molecular Weight | N/A |
CAS No. | 1709815-23-5 |
store at low temperature
store at -80°C
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Emapalumab 1709815-23-5 Immunology/Inflammation Neuroscience COX NI-0501 NI0501 NI 0501 inhibitor inhibit