Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 212.00 | |
5 mg | In stock | $ 397.00 | |
10 mg | In stock | $ 589.00 | |
25 mg | In stock | $ 945.00 | |
50 mg | In stock | $ 1,280.00 | |
100 mg | In stock | $ 1,730.00 | |
500 mg | In stock | $ 3,460.00 |
Description | Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer. |
In vitro | Compound TPX-0046 (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells[1]. |
In vivo | Compound TPX-0046 (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice[1]. |
Molecular Weight | 424.43 |
Formula | C21H21FN6O3 |
CAS No. | 2411115-73-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. More
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Compound TPX-0046 2411115-73-4 Apoptosis Tyrosine Kinase/Adaptors c-RET CompoundTPX0046 Compound TPX 0046 Compound TPX0046 inhibitor inhibit