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Anti-ATP1B4 Antibody (4E867)
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Catalog No. TMAY-02439
Alias ATPase, Na+/K+ transporting, β 4 polypeptide, ATPase, Na+/K+ transporting, beta 4 polypeptide
Anti-ATP1B4 Antibody (4E867) is a Mouse antibody targeting ATP1B4. Anti-ATP1B4 Antibody (4E867) can be used in ELISA.
Anti-ATP1B4 Antibody (4E867)
Anti-ATP1B4 Antibody (4E867)
😃Good
Catalog No. TMAY-02439Alias ATPase, Na+/K+ transporting, β 4 polypeptide, ATPase, Na+/K+ transporting, beta 4 polypeptide
Anti-ATP1B4 Antibody (4E867) is a Mouse antibody targeting ATP1B4. Anti-ATP1B4 Antibody (4E867) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ATP1B4 Antibody (4E867) is a Mouse antibody targeting ATP1B4. Anti-ATP1B4 Antibody (4E867) can be used in ELISA. |
| Synonyms | ATPase, Na+/K+ transporting, β 4 polypeptide, ATPase, Na+/K+ transporting, beta 4 polypeptide |
| Ig Type | Mouse IgG2b |
| Clone | 4E867 |
| Reactivity | Human |
| Specificity | Human ATP1B4 No cross-reactivity in ELISA with E.coli cell lysate |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ATP1B4 (mature form, NP_036201.1; Tyr 132-Thr 357). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ATP1B4 is a member of the X(+)/potassium ATPases subunit beta family. It is highly expressed in skeletal muscle and at a lower level in heart. ATP1B4 gene can be found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na, K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. ATP1B4 may act as a transcriptional coregulator during muscle development through its interaction with SNW1. Na+, K+-ATPase is an important regulator of intracellular electrolyte levels in most mammalian cells. It is a Mg2+-dependent transport pump responsible for maintaining the low intracellular Na+:K+ ratio that is essential for cell homeostasis and physiological function. It catalyzes the active uptake of K+ and extrusion of Na+ at the expense of hydrolyzing ATP with a stoichiometry of 3 Na+ for 2 K+. ATP1B4 has lost its ancestral function as a Na,K-ATPase beta-subunit. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ATP1B4 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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