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Anti-pro Caspase 7 Antibody (8A709)
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Catalog No. TMAC-03428
Alias ICE-like apoptotic protease 3, ICE-LAP3, CMH-1, Caspase-7 subunit p11, CASP7_HUMAN, CASP-7, CASP7, Apoptotic protease Mch-3, apoptosis-related cysteine peptidase
Anti-pro Caspase 7 Antibody (8A709) is a Rabbit antibody targeting pro Caspase 7. Anti-pro Caspase 7 Antibody (8A709) can be used in ICC/IF,IHC,WB.
Anti-pro Caspase 7 Antibody (8A709)
Anti-pro Caspase 7 Antibody (8A709)
😃Good
Catalog No. TMAC-03428Alias ICE-like apoptotic protease 3, ICE-LAP3, CMH-1, Caspase-7 subunit p11, CASP7_HUMAN, CASP-7, CASP7, Apoptotic protease Mch-3, apoptosis-related cysteine peptidase
Anti-pro Caspase 7 Antibody (8A709) is a Rabbit antibody targeting pro Caspase 7. Anti-pro Caspase 7 Antibody (8A709) can be used in ICC/IF,IHC,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-pro Caspase 7 Antibody (8A709) is a Rabbit antibody targeting pro Caspase 7. Anti-pro Caspase 7 Antibody (8A709) can be used in ICC/IF,IHC,WB. |
| Synonyms | ICE-like apoptotic protease 3, ICE-LAP3, CMH-1, Caspase-7 subunit p11, CASP7_HUMAN, CASP-7, CASP7, Apoptotic protease Mch-3, apoptosis-related cysteine peptidase |
| Ig Type | IgG |
| Clone | 8A709 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of pro Caspase 7 on human lung lysates using anti-pro Caspase 7 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-pro Caspase 7 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-pro Caspase 7 antibody. Counter stained with hematoxylin. 4. ICC staining pro Caspase 7 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining pro Caspase 7 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 34 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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