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Anti-TIMP-1 Antibody (7K734)

😃Good
Catalog No. TMAH-01175
Alias TIMP-1, TIMP metallopeptidase inhibitor 1, TIMP, HCI, EPO, EPA, CLGI

Anti-TIMP-1 Antibody (7K734) is a Mouse antibody targeting TIMP-1. Anti-TIMP-1 Antibody (7K734) can be used in ELISA, WB, IHC.

Anti-TIMP-1 Antibody (7K734)

Anti-TIMP-1 Antibody (7K734)

😃Good
Catalog No. TMAH-01175Alias TIMP-1, TIMP metallopeptidase inhibitor 1, TIMP, HCI, EPO, EPA, CLGI
Anti-TIMP-1 Antibody (7K734) is a Mouse antibody targeting TIMP-1. Anti-TIMP-1 Antibody (7K734) can be used in ELISA, WB, IHC.
Pack SizePriceAvailabilityQuantity
50 μg$209 7-10 days
100 μg$348 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Mouse Monoclonal

Application: ELISA, WB, IHC

Reactivity: Human, Mouse
AliasTIMP-1, TIMP metallopeptidase inhibitor 1, TIMP, HCI, EPO, EPA, CLGI
Ig Type
IgG2a
Clone
7K734
Reactivity
Human, Mouse
Verified Activity
1. Western Blot
-All lanes:Mouse anti-Human Timp1 monoclonal antibody at 1μg/ml
-Lane 1: HepG-2 cell lysate
-Predicted band size : 23 kDa
-Observed band size : 23 kDa
-Additional bands at:50KD
2. Western Blot
-All lanes: Mouse anti-Human Timp1 monoclonal antibody at 1μg/ml
-Lane 1: TIMP1 transfected pichia Yeast cell lysate
-Predicted band size : 23 kDa
-Observed band size:23 kDa
3. Immunohistochemistry of paraffin-embedded human prostate cancer using TMAH-01175 at dilution of 1:100
Application
ELISA, WB, IHC
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationSecreted.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
FormulationPreservative: 15mmol/L NaN3. Constituents: 0.1mol/L Nacl.
Purity>95%
Research BackgroundMetalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human Timp 1 Protein
Antigen Species
Human
Gene ID
7076
Uniprot ID
Biology Area
Cardiovascular
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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