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Anti-TIMP-1 Antibody (7K734) is a Mouse antibody targeting TIMP-1. Anti-TIMP-1 Antibody (7K734) can be used in ELISA, WB, IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μg | $209 | 7-10 days | |
100 μg | $348 | 7-10 days |
Description | Antibody Type: Mouse Monoclonal Application: ELISA, WB, IHC Reactivity: Human, Mouse |
Alias | TIMP-1, TIMP metallopeptidase inhibitor 1, TIMP, HCI, EPO, EPA, CLGI |
Ig Type | IgG2a |
Clone | 7K734 |
Reactivity | Human, Mouse |
Verified Activity | 1. Western Blot -All lanes:Mouse anti-Human Timp1 monoclonal antibody at 1μg/ml -Lane 1: HepG-2 cell lysate -Predicted band size : 23 kDa -Observed band size : 23 kDa -Additional bands at:50KD 2. Western Blot -All lanes: Mouse anti-Human Timp1 monoclonal antibody at 1μg/ml -Lane 1: TIMP1 transfected pichia Yeast cell lysate -Predicted band size : 23 kDa -Observed band size:23 kDa 3. Immunohistochemistry of paraffin-embedded human prostate cancer using TMAH-01175 at dilution of 1:100 |
Application | ELISA, WB, IHC |
Antibody Type | Monoclonal |
Host Species | Mouse |
Subcellular Localization | Secreted. |
Construction | Hybridoma Monoclonal Antibody |
Purification | Protein G purified |
Appearance | Liquid |
Formulation | Preservative: 15mmol/L NaN3. Constituents: 0.1mol/L Nacl. |
Purity | >95% |
Research Background | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human Timp 1 Protein |
Antigen Species | Human |
Gene ID | 7076 |
Uniprot ID | |
Biology Area | Cardiovascular |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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