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Anti-TM7SF2 Polyclonal Antibody

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Catalog No. TMAB-01864
Alias Transmembrane 7 superfamily member 2, TM7SF2, Sterol C14 reductase, Putative sterol reductase SR 1, NET47, ERG24, DHCR14A, delta-14-SR, delta(14) sterol reductase, delta 14 SR, C 14 sterol reductase, Another new gene 1 protein, ANG1

Anti-TM7SF2 Polyclonal Antibody is a Rabbit antibody targeting TM7SF2. Anti-TM7SF2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-TM7SF2 Polyclonal Antibody

Anti-TM7SF2 Polyclonal Antibody

😃Good
Catalog No. TMAB-01864Alias Transmembrane 7 superfamily member 2, TM7SF2, Sterol C14 reductase, Putative sterol reductase SR 1, NET47, ERG24, DHCR14A, delta-14-SR, delta(14) sterol reductase, delta 14 SR, C 14 sterol reductase, Another new gene 1 protein, ANG1
Anti-TM7SF2 Polyclonal Antibody is a Rabbit antibody targeting TM7SF2. Anti-TM7SF2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2207-10 days
100 μL$3747-10 days
200 μL$5287-10 days
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Product Introduction

Bioactivity
Description
Anti-TM7SF2 Polyclonal Antibody is a Rabbit antibody targeting TM7SF2. Anti-TM7SF2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
SynonymsTransmembrane 7 superfamily member 2, TM7SF2, Sterol C14 reductase, Putative sterol reductase SR 1, NET47, ERG24, DHCR14A, delta-14-SR, delta(14) sterol reductase, delta 14 SR, C 14 sterol reductase, Another new gene 1 protein, ANG1
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Cow,Rabbit,Sheep)
Verified Activity
1. Sample:
Lane 1: Mouse Adrenal gland tissue lysates
Lane 2: Rat Adrenal gland tissue lysates
Primary: Anti-TM7SF2 (TMAB-01864) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kDa
Observed band size: 58 kDa
2. Paraformaldehyde-fixed, paraffin embedded (Human prostatic cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (TM7SF2) Polyclonal Antibody, Unconjugated (TMAB-01864) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded (Human adrenal gland); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (TM7SF2) Polyclonal Antibody, Unconjugated (TMAB-01864) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded (Human heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (TM7SF2) Polyclonal Antibody, Unconjugated (TMAB-01864) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMicrosome membrane; Multi-pass membrane protein (By similarity). Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundInvolved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TM7SF2/DHCR14A
Antigen Species
Human
Gene Name
TM7SF2
Gene ID
Protein Name
delta(14)-sterol reductase TM7SF2
Uniprot ID
Function
Involved in the conversion of lanosterol to cholesterol.
Chemical Properties
Molecular WeightTheoretical: 46 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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