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Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody
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Catalog No. TMAC-00786
Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDK1 (Thr14). Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody can be used in WB.
Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody
Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody
😃Good
Catalog No. TMAC-00786
Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDK1 (Thr14). Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDK1 (Thr14). Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1, B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phospho rylation site of threonine14(E-G-T(p)-Y-G) derived from Human CDK1/CDC2 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 34 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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