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Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody (Synonyms: p-CDK1 (Thr14), p-CDK1 (T14), CDK1 (p-Thr14), CDK1 (...)

Catalog No. TMAC-00786 Copy Product Info
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Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDK1 (Thr14). Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody can be used in WB.

Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-00786
Synonyms p-CDK1 (Thr14), p-CDK1 (T14), CDK1 (p-Thr14), CDK1 (p-T14)

Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDK1 (Thr14). Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody can be used in WB.

Anti-Phospho-CDK1
(Thr14) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDK1 (Thr14). Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody can be used in WB.
Synonymsp-CDK1 (Thr14), p-CDK1 (T14), CDK1 (p-Thr14), CDK1 (p-T14)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from HepG2 cells treated with Forskolin using Phospho-CDK1/CDC2 (Thr14) antibody TMAC-00786. The lane on the right is treated with the antigen-specific peptide.
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundSerine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1, B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phospho rylation site of threonine14(E-G-T(p)-Y-G) derived from Human CDK1/CDC2
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 34 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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