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Anti-Carbonic Anhydrase 4 Antibody (2I446) is a Rabbit antibody targeting Carbonic Anhydrase 4. Anti-Carbonic Anhydrase 4 Antibody (2I446) can be used in ELISA,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-Carbonic Anhydrase 4 Antibody (2I446) is a Rabbit antibody targeting Carbonic Anhydrase 4. Anti-Carbonic Anhydrase 4 Antibody (2I446) can be used in ELISA,IHC-P. |
Alias | RP23-167D6.1, carbonic anhydrase IV, Car4, Ca4, AW456718 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 2I446 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human CA4 in human lung with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to pulmonary capillaries. 2. Immunochemical staining of human CA4 in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to renal tubules. |
Application | ELISA,IHC-P |
Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase IV / CA4 (rh Carbonic Anhydrase IV / CA4; NP_000708.1Met1-Lys283). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase IV (CAIV) is a membrane-associated enzyme anchored to plasma membrane surfaces by a phosphatidylinositol glycan linkage. CAIV is a high-activity isozyme in CO2hydration comparable to that of CAII. Furthermore, CAIV is more active in HCO3-dehydration than is CAII. However, the esterase activity of CAIV is decreased 150-fold compared to CAII. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Carbonic Anhydrase IV / CA4 protein |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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