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Anti-Carbonic Anhydrase 4 Antibody (2I446)

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Catalog No. TMAY-00874
Alias RP23-167D6.1, carbonic anhydrase IV, Car4, Ca4, AW456718

Anti-Carbonic Anhydrase 4 Antibody (2I446) is a Rabbit antibody targeting Carbonic Anhydrase 4. Anti-Carbonic Anhydrase 4 Antibody (2I446) can be used in ELISA,IHC-P.

Anti-Carbonic Anhydrase 4 Antibody (2I446)

Anti-Carbonic Anhydrase 4 Antibody (2I446)

😃Good
Catalog No. TMAY-00874Alias RP23-167D6.1, carbonic anhydrase IV, Car4, Ca4, AW456718
Anti-Carbonic Anhydrase 4 Antibody (2I446) is a Rabbit antibody targeting Carbonic Anhydrase 4. Anti-Carbonic Anhydrase 4 Antibody (2I446) can be used in ELISA,IHC-P.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Carbonic Anhydrase 4 Antibody (2I446) is a Rabbit antibody targeting Carbonic Anhydrase 4. Anti-Carbonic Anhydrase 4 Antibody (2I446) can be used in ELISA,IHC-P.
AliasRP23-167D6.1, carbonic anhydrase IV, Car4, Ca4, AW456718
Ig Type
Monoclonal Rabbit IgG
Clone
2I446
Reactivity
Human
Verified Activity
1. Immunochemical staining of human CA4 in human lung with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to pulmonary capillaries.

2. Immunochemical staining of human CA4 in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to renal tubules.
Application
ELISA,IHC-P
Recommended Dose
ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase IV / CA4 (rh Carbonic Anhydrase IV / CA4; NP_000708.1Met1-Lys283).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase IV (CAIV) is a membrane-associated enzyme anchored to plasma membrane surfaces by a phosphatidylinositol glycan linkage. CAIV is a high-activity isozyme in CO2hydration comparable to that of CAII. Furthermore, CAIV is more active in HCO3-dehydration than is CAII. However, the esterase activity of CAIV is decreased 150-fold compared to CAII.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Carbonic Anhydrase IV / CA4 protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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