Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

D-myo-Inositol-1,4,5-triphosphate trisodium

😃Good
Catalog No. T35935Cas No. 141611-10-1
Alias Ins(1,4,5)-P3 trisodium, Ins(1,4,5)P3, Inositol 1,4,5-trisphosphate trisodium, D-myo-Inositol-1,4,5-triphosphate (sodium salt)

D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by the phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-bisphosphate. It binds to Ins(1,4,5)P3 receptors, resulting in the opening of calcium channels and an increase in intracellular calcium.

D-myo-Inositol-1,4,5-triphosphate trisodium

D-myo-Inositol-1,4,5-triphosphate trisodium

😃Good
Catalog No. T35935Alias Ins(1,4,5)-P3 trisodium, Ins(1,4,5)P3, Inositol 1,4,5-trisphosphate trisodium, D-myo-Inositol-1,4,5-triphosphate (sodium salt)Cas No. 141611-10-1
D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by the phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-bisphosphate. It binds to Ins(1,4,5)P3 receptors, resulting in the opening of calcium channels and an increase in intracellular calcium.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 μg$15935 days35 days
5 mg$1,23035 days35 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Appearance:Solid
Contact us for more batch information

Resource Download

Product Introduction

Bioactivity
Description
D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by the phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-bisphosphate. It binds to Ins(1,4,5)P3 receptors, resulting in the opening of calcium channels and an increase in intracellular calcium.
In vitro
The dissociation constant (KD) for D-myo-Inositol-1,4,5-trisphosphate (As an inositol phosphate derivative) complexed with Pr55Gag is 2170 μM. The binding affinities of D-myo-Inositol-1,4,5-trisphosphate for matrix (MA) with KD=568 μM.[4]
SynonymsIns(1,4,5)-P3 trisodium, Ins(1,4,5)P3, Inositol 1,4,5-trisphosphate trisodium, D-myo-Inositol-1,4,5-triphosphate (sodium salt)
Chemical Properties
Molecular Weight489.06
FormulaC6H15Na3O15P3
Cas No.141611-10-1
SmilesO=P(O)(O)O[C@H]1[C@@H]([C@H]([C@H]([C@H]([C@@H]1O)OP(O)(O)=O)O)O)OP(O)(O)=O.[Na].[Na].[Na]
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
PBS (pH 7.2): 50 mg/mL (102.24 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)
1mg5mg10mg50mg
1 mM2.0447 mL10.2237 mL20.4474 mL102.2369 mL
5 mM0.4089 mL2.0447 mL4.0895 mL20.4474 mL
10 mM0.2045 mL1.0224 mL2.0447 mL10.2237 mL
20 mM0.1022 mL0.5112 mL1.0224 mL5.1118 mL
50 mM0.0409 mL0.2045 mL0.4089 mL2.0447 mL
100 mM0.0204 mL0.1022 mL0.2045 mL1.0224 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy D-myo-Inositol-1,4,5-triphosphate trisodium | purchase D-myo-Inositol-1,4,5-triphosphate trisodium | D-myo-Inositol-1,4,5-triphosphate trisodium cost | order D-myo-Inositol-1,4,5-triphosphate trisodium | D-myo-Inositol-1,4,5-triphosphate trisodium chemical structure | D-myo-Inositol-1,4,5-triphosphate trisodium in vitro | D-myo-Inositol-1,4,5-triphosphate trisodium formula | D-myo-Inositol-1,4,5-triphosphate trisodium molecular weight