Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact UsQuotation
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

D-myo-Inositol-1,4,5-triphosphate trisodium

😃Good
Catalog No. T35935Cas No. 141611-10-1
Alias Ins(1,4,5)-P3 trisodium, Ins(1,4,5)P3, Inositol 1,4,5-trisphosphate trisodium, D-myo-Inositol-1,4,5-triphosphate (sodium salt)

D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by the phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-bisphosphate. It binds to Ins(1,4,5)P3 receptors, resulting in the opening of calcium channels and an increase in intracellular calcium.

D-myo-Inositol-1,4,5-triphosphate trisodium
Other Forms of D-myo-Inositol-1,4,5-triphosphate trisodium:

D-myo-Inositol-1,4,5-triphosphate trisodium

😃Good
Catalog No. T35935Alias Ins(1,4,5)-P3 trisodium, Ins(1,4,5)P3, Inositol 1,4,5-trisphosphate trisodium, D-myo-Inositol-1,4,5-triphosphate (sodium salt)Cas No. 141611-10-1
D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by the phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-bisphosphate. It binds to Ins(1,4,5)P3 receptors, resulting in the opening of calcium channels and an increase in intracellular calcium.
Pack SizePriceAvailabilityQuantity
500 μg$15935 days
5 mg$1,23035 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Batch Information

Select Batch
Contact us for more batch information

Resource Download

COA

Product Introduction

Bioactivity
Description
D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by the phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-bisphosphate. It binds to Ins(1,4,5)P3 receptors, resulting in the opening of calcium channels and an increase in intracellular calcium.
In vitro
The dissociation constant (KD) for D-myo-Inositol-1,4,5-trisphosphate (As an inositol phosphate derivative) complexed with Pr55Gag is 2170 μM. The binding affinities of D-myo-Inositol-1,4,5-trisphosphate for matrix (MA) with KD=568 μM.[4]
SynonymsIns(1,4,5)-P3 trisodium, Ins(1,4,5)P3, Inositol 1,4,5-trisphosphate trisodium, D-myo-Inositol-1,4,5-triphosphate (sodium salt)
Chemical Properties
Molecular Weight489.06
FormulaC6H15Na3O15P3
Cas No.141611-10-1
SmilesO=P(O)(O)O[C@H]1[C@@H]([C@H]([C@H]([C@H]([C@@H]1O)OP(O)(O)=O)O)O)OP(O)(O)=O.[Na].[Na].[Na]
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
PBS (pH 7.2): 50 mg/mL (102.24 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)
1mg5mg10mg50mg
1 mM2.0447 mL10.2237 mL20.4474 mL102.2369 mL
5 mM0.4089 mL2.0447 mL4.0895 mL20.4474 mL
10 mM0.2045 mL1.0224 mL2.0447 mL10.2237 mL
20 mM0.1022 mL0.5112 mL1.0224 mL5.1118 mL
50 mM0.0409 mL0.2045 mL0.4089 mL2.0447 mL
100 mM0.0204 mL0.1022 mL0.2045 mL1.0224 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Ins(1,4,5)-P3Inositol 1,4,5-trisphosphateD-myo-Inositol-1,4,5-triphosphate trisodiumD-myo-Inositol-1,4,5-triphosphateCalciumChannelCalcium Channel
Related Tags: buy D-myo-Inositol-1,4,5-triphosphate trisodium | purchase D-myo-Inositol-1,4,5-triphosphate trisodium | D-myo-Inositol-1,4,5-triphosphate trisodium cost | order D-myo-Inositol-1,4,5-triphosphate trisodium | D-myo-Inositol-1,4,5-triphosphate trisodium chemical structure | D-myo-Inositol-1,4,5-triphosphate trisodium in vitro | D-myo-Inositol-1,4,5-triphosphate trisodium formula | D-myo-Inositol-1,4,5-triphosphate trisodium molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.