Shopping Cart
- Remove All
Your shopping cart is currently empty
(148)
Endocrinology/HormonesEstrogen/progestogen Receptor
Estrogen receptors are a group of proteins found inside cells. They are receptors that are activated by the hormone estrogen (17β-estradiol). Two classes of estrogen receptor exist: ER, which is a member of the nuclear hormone family of intracellular receptors, and GPER (GPR30), which is a member of the rhodopsin-like family of G protein-coupled receptors.The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated by the steroid hormone progesterone.
Tamoxifen
T690610540-29-1
Tamoxifen is an orally active selective estrogen receptor modulator (SERM) that acts as an estrogen antagonist in breast cells and an agonist in bone, liver, and uterine cells. It can be used to induce gene knockout and liver injury models in mice, and also exhibits multiple biological activities, including activation of Hsp90, induction of autophagy and apoptosis, and inhibition of EBOV and MARV viral infections.
- $30
Size
QTY
4-Hydroxytamoxifen
T442068047-06-3
4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer research.
- $64
Size
QTY
Fulvestrant
T2146129453-61-8
Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30. Fulvestrant has antitumor activity, inhibiting cell proliferation and inducing apoptosis and autophagy.
- $42
Size
QTY
SLU-PP-332
T77577303760-60-3
SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ, exhibiting EC50 values of 98, 230, and 430 nM, respectively. SLU-PP-332 enhances mitochondrial function and cellular respiration, increases type IIa oxidized skeletal muscle fibers, and enhances exercise tolerance in skeletal muscle cell lines. It has potential applications in the study of metabolic diseases, improvement of muscle function, and amelioration of metabolic disorders and aging.
- $32
Size
QTY
27-Hydroxycholesterol
TQ027420380-11-4
27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) is a selective modulator of estrogen receptor and an agonist of the liver X receptor.
- $47
Size
QTY
Fulvestrant-d3
TMIJ-0244
Fulvestrant-d3 is a isotope labeled compound of Fulvestrant.Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist and GPR30 agonist that inhibits cell proliferation and induces apoptosis and autophagy.
- Inquiry Price
Size
QTY
(E/Z)-4-Hydroxytamoxifen
T674368392-35-8
(E Z)-4-Hydroxytamoxifen (Afimoxifene) is a novel estrogen inhibitor, commonly used in research for various estrogen-dependent conditions, including cyclic mastalgia and gynecomastia.
- $47
Size
QTY
Kaempferol
T2177520-18-3
Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities.
- $33
Size
QTY
Mifepristone
T110284371-65-3
Mifepristone (C-1073) is a progesterone-receptor (IC50=0.2 nM) and glucocorticoid-receptor antagonist (IC50=2.6 nM). Mifepristone is used to terminate pregnancy, treat uterine fibroids, and treat endometriosis.
- $33
Size
QTY
Estradiol
T104850-28-2
Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradiol upregulates IL-6 expression through estrogen receptor beta (ERβ).
- $30
Size
QTY
Indazole-Cl
T25534848142-62-1In house
Indazole-Cl is a selective ERß agonist and a selective estrogen receptor modifier (SERM).
- $117
Size
QTY
XR 5944
T35187343247-32-5In house
XR 5944 is an antitumor compound that targets DNA, is a topoisomerase inhibitor, inhibits ER activity, and can be used to study colon and lung cancer.
- $226
Size
QTY
Elacestrant
T13674722533-56-4
Elacestrant (RAD1901) with IC50s of 48 and 870 nM for ERα and ERβ, respectively.Elacestrant is an orally available selective estrogen receptor degrader .
- $147
Size
QTY
Liquiritigenin
T3325578-86-9
Liquiritigenin (4',7-Dihydroxyflavanone), a flavonoid aglycone from licorice, is a highly selective estrogen receptor β (ERβ) agonist.
- $35
Size
QTY
Bazedoxifene acetate
T2544198481-33-3
Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM).
- $39
Size
QTY
Giredestrant
T113991953133-47-5
Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist.
- $119
Size
QTY
GSK5182
T8370877387-37-6
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
- $48
Size
QTY
(+)-Medicarpin
T1376833983-39-0
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium floribundum. It potently inhibits osteoclastogenesis and facilitates bone healing and increased bone mass through osteoblast differentiation, mediated by the estrogen receptor (ER) β.
- $141
Size
QTY
Progesterone
T047857-83-0
Progesterone is a steroid hormone that regulates the menstrual cycle and is essential for pregnancy. It is also commonly used to induce melasma models.
- $38
Size
QTY
kaempferide
T3806491-54-3
kaempferide (4'-Methylkaempferol) inhibits the proliferation of native and estrogen receptor beta overexpressing colon cancer cells through a mechanism not mediated by ligand binding dependent estrogen receptor activation.
- $35
Size
QTY
AZD9496
T39751639042-08-2
AZD9496 is an orally available selective estrogen receptor(ERα) antagonist, with potential antineoplastic activity.
- $51
Size
QTY
Melatonin
T165973-31-4
Melatonin (Melatonine) is a natural hormone secreted by the pineal gland that activates melatonin receptors. Melatonin is a hormone that regulates the biological clock and also has antioxidant and anti-inflammatory activities.
- $31
Size
QTY
NXT629
T122781454925-59-7
NXT629 is a selective and highly efficient PPAR-α antagonist with anticancer activity. It inhibits PPARδ, PPARγ, Erβ, GR, and TRβ and can be used in research on ovarian cancer and melanoma.
- $189
Size
QTY
Go to page 1
Page of 3
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.