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PRL-2 Protein, Human, Recombinant (His)
(Synonyms: PTP4A2, PTP(CAAXII), Protein-tyrosine phosphatase of regenerating liver 2, Protein-tyrosine phosphatase 4a2, Protein tyrosine phosphatase type IVA 2, PRL-2, OV-1, HU-PP-1) Copy Product InfoSynonyms: PTP4A2, PTP(CAAXII), Protein-tyrosine phosphatase of regenerating liver 2, Protein-tyrosine phosphatase 4a2, Protein tyrosine phosphatase type IVA 2, PRL-2, OV-1, HU-PP-1
Catalog No. TMPJ-00053 Copy Product Info
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $72 | 35 days | 35 days | |
| 10 μg | $116 | 35 days | 35 days | |
| 20 μg | $176 | 35 days | 35 days | |
| 50 μg | $310 | 35 days | 35 days | |
| 100 μg | $532 | 35 days | 35 days | |
| 200 μg | $919 | 35 days | 35 days | |
| 500 μg | $1,900 | 35 days | 35 days | |
| 1 mg | $2,730 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-6xHis |
| Accession Number | Q12974 |
| Amino Acid | Met1-Gln167 |
| Construction | Met1-Gln167 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM HEPES, 150 mM NaCl, 10 mM β-ME, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | PTP4A2, PTP(CAAXII), Protein-tyrosine phosphatase of regenerating liver 2, Protein-tyrosine phosphatase 4a2, Protein tyrosine phosphatase type IVA 2, PRL-2, OV-1, HU-PP-1 |
| Research Background |
| Molecular Weight | 18 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: PRL-2 Protein, Human, Recombinant (His) chemical structure | PRL-2 Protein, Human, Recombinant (His) molecular weight
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