Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pegdinetanib (BMS-844203; CT-322) is a selective inhibitor targeting VEGFR-2 (VEGFR), exhibiting dissociation constants (Kd) of 11 nM and 250 nM and half-maximal inhibitory concentrations (IC50) of 16 nM and 240 nM for human and murine VEGFR-2, respectively. It demonstrates no affinity for VEGFR-1 or VEGFR-3. Its effectiveness extends to antitumor activity [1].
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Description | Pegdinetanib (BMS-844203; CT-322) is a selective inhibitor targeting VEGFR-2 (VEGFR), exhibiting dissociation constants (Kd) of 11 nM and 250 nM and half-maximal inhibitory concentrations (IC50) of 16 nM and 240 nM for human and murine VEGFR-2, respectively. It demonstrates no affinity for VEGFR-1 or VEGFR-3. Its effectiveness extends to antitumor activity [1]. |
Molecular Weight | N/A |
CAS No. | 906450-24-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pegdinetanib 906450-24-6 inhibitor inhibit