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Betamethasone dipropionate

Name: Betamethasone dipropionate
Brand: TargetMol
SKU: T1559
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T1559Cas No. 5593-20-4

Alias SCH 11460, Diprosone, Diprolene AF, Diprolene, Betamethasone 17,21-dipropionate

Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate (SCH 11460) binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

Betamethasone dipropionate

🥰Excellent

Purity: 99.59%

Catalog No. T1559Alias SCH 11460, Diprosone, Diprolene AF, Diprolene, Betamethasone 17,21-dipropionateCas No. 5593-20-4

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$30	In Stock	In Stock
500 mg	$68	In Stock	In Stock
1 g	$97	-	In Stock
1 mL x 10 mM (in DMSO)	$52	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.59%

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description

Synonyms

SCH 11460, Diprosone, Diprolene AF, Diprolene, Betamethasone 17,21-dipropionate

Chemical Properties

Molecular Weight	504.59
Formula	C₂₈H₃₇FO₇
Cas No.	5593-20-4
Smiles	C(COC(CC)=O)(=O)[C@]1(OC(CC)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
Relative Density.	1.24g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 66 mg/mL (130.8 mM), Sonication is recommended.

DMSO: 101 mg/mL (200.16 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (6.54 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9818 mL	9.9090 mL	19.8181 mL	99.0904 mL
5 mM	0.3964 mL	1.9818 mL	3.9636 mL	19.8181 mL
10 mM	0.1982 mL	0.9909 mL	1.9818 mL	9.9090 mL
20 mM	0.0991 mL	0.4955 mL	0.9909 mL	4.9545 mL
50 mM	0.0396 mL	0.1982 mL	0.3964 mL	1.9818 mL
100 mM	0.0198 mL	0.0991 mL	0.1982 mL	0.9909 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc