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Anti-CD86 Antibody-PE (2A700)

🥰Excellent
Catalog No. TMAY-03072P

Anti-CD86 Antibody-PE (2A700) is a PE-conjugated Rabbit antibody targeting CD86. Anti-CD86 Antibody-PE (2A700) can be used in FCM.

Anti-CD86 Antibody-PE (2A700)

Anti-CD86 Antibody-PE (2A700)

🥰Excellent
Catalog No. TMAY-03072P
Anti-CD86 Antibody-PE (2A700) is a PE-conjugated Rabbit antibody targeting CD86. Anti-CD86 Antibody-PE (2A700) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-CD86 Antibody-PE (2A700) is a PE-conjugated Rabbit antibody targeting CD86. Anti-CD86 Antibody-PE (2A700) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
2A700
Reactivity
Mouse
Verified Activity
Flow cytometric analysis of Mouse-CD86 expression on LPS-stimulated BABL/c splenocytesCells were stained with PE-conjugated anti-Mouse-CD86. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD86 (rM CD86; TMPY-01206; NP_062261.3; Met1-Glu245) and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundCD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated/FITC
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Mouse CD86 Protein (TMPY-01206)
Antigen Species
Mouse
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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