HB-EGF Protein, Mouse, Recombinant

Name: HB-EGF Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPS-00047
Price: 85 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Heparin Binding EGF-like growth factor, HEGFL, HBEGF, DTR, Diphtheria toxin receptor) Copy Product Info

Synonyms: Heparin Binding EGF-like growth factor, HEGFL, HBEGF, DTR, Diphtheria toxin receptor

Catalog No. TMPS-00047 Copy Product Info

HB-EGF Protein, Mouse, Recombinant is expressed in E. coli. The accession number is Q06186.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$85	-	In Stock
10 µg	$138	-	In Stock
20 µg	$197	7-10 days	7-10 days
50 µg	$339	-	In Stock
100 µg	$533	7-10 days	7-10 days
200 µg	$843	7-10 days	7-10 days
500 µg	$1,550	7-10 days	7-10 days
1 mg	$2,460	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:> 97% as analyzed by SDS-PAGE > 97% as analyzed by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Fully biologically active when compared to standard. The ED 50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 × 10 6 IU/mg.
Description	HB-EGF Protein, Mouse, Recombinant is expressed in E. coli. The accession number is Q06186.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	Q06186
Construction	Asp63-Leu148
Protein Purity	> 97% as determined by SDS-PAGE; > 97% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in 10 mM PB, 500 mM NaCl, pH7.4.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water or aqueous buffer containing 0.1% BSA. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Heparin Binding EGF-like growth factor, HEGFL, HBEGF, DTR, Diphtheria toxin receptor
Research Background	Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins. HB-EGF-like growth factor is synthesized as a membrane-anchored mitogenic and chemotactic glycoprotein. An epidermal growth factor produced by monocytes and macrophages, due to an affinity for heparin is termed HB-EGF. It has been shown to play a role in wound healing, cardiac hypertrophy and heart development and function. The transmembrane form of HB-EGF is the unique receptor for diptheria toxin and functions in juxtacrine signaling in cells. Both forms of HB-EGF participate in normal physiological processes and in pathological processes including tumor progression and metastasis, organ hyperplasia, and atherosclerotic disease. HB-EGF can bind two locations on cell surfaces, heparan sulfate proteoglycans and EGF-receptor effecting cell to cell interactions.

Chemical Properties

Molecular Weight

9.8 kDa (Predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.