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THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, aids in the synthesis of PROTAC K-Ras Degrader-1[1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $39 | 5 days |
Description | THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, aids in the synthesis of PROTAC K-Ras Degrader-1[1]. |
In vitro | PROTAC K-Ras Degrader-1 is a potent K-Ras degrader based on PROTAC, exhibiting ≥70% degradation efficacy in SW1573 cells[1]. PROTACs contain two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest, leveraging the ubiquitin-proteasome system for selective protein degradation. |
Molecular Weight | 391.5 |
Formula | C19H37NO7 |
Cas No. | 2378261-81-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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