Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sp-Adenosine-5'-O-(1-thiotriphosphate) (Sp-ATP-α-S), an isomer of the ATP-α-S sulfur-containing nucleotide derivative and a purinergic P2Y1 receptor agonist, effectively increases calcium mobilization in HEK293 cells harboring the P2Y1 receptor with an EC50 of 9.4 nM for the human receptor. It also inhibits ADP-induced human isolated platelet aggregation with a Ki value of 4 μM and prompts relaxation in carbamoylcholine-tightened guinea pig taenia coli, achieving an EC50 of 426 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | Sp-Adenosine-5'-O-(1-thiotriphosphate) (Sp-ATP-α-S), an isomer of the ATP-α-S sulfur-containing nucleotide derivative and a purinergic P2Y1 receptor agonist, effectively increases calcium mobilization in HEK293 cells harboring the P2Y1 receptor with an EC50 of 9.4 nM for the human receptor. It also inhibits ADP-induced human isolated platelet aggregation with a Ki value of 4 μM and prompts relaxation in carbamoylcholine-tightened guinea pig taenia coli, achieving an EC50 of 426 nM. |
Synonyms | Sp-ATP-α-S |
Molecular Weight | 611.18 |
Formula | C10H12N5O12P3S.4Na |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Soluble
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Sp-Adenosine-5'-O-(1-thiotriphosphate) sodium Sp-ATP-α-S inhibitor inhibit